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. 1991 Jul;65(7):3928–3931. doi: 10.1128/jvi.65.7.3928-3931.1991

v-myb and v-ets cooperate for the mitogenic stimulation of primary fibroblasts by avian E26 retrovirus.

P Ravel-Chapuis 1, D Leprince 1, B Pain 1, R Li 1, C Domenget 1, D Stehelin 1, J Samarut 1, P Jurdic 1
PMCID: PMC241431  PMID: 1645800

Abstract

By using a series of deletion mutants, we have shown that the stimulation of fibroblast growth by E26 requires the cooperation of the two oncogenes, v-myb and v-ets, fused in the nuclear viral product. Of the two DNA-binding domains, only one must be present to promote anchorage-independent growth, whereas that of v-myb is required to allow growth in low serum medium. Furthermore, the v-ets oncogene comprises multifunctional domains.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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