Skip to main content
Postgraduate Medical Journal logoLink to Postgraduate Medical Journal
. 1983 Feb;59(688):86–87. doi: 10.1136/pgmj.59.688.86

The pharmacokinetics of lysine theophylline, a new soluble theophylline, in human volunteers.

A Johnston, M E Aldhous, A Hedges, K Weerasuriya, A Freedman, P Turner
PMCID: PMC2417382  PMID: 6844192

Abstract

A comparative study of the pharmacokinetics of lysine theophylline and aminophylline in normal subjects reveals no significant difference. If lysine theophylline is shown to have the same clinical efficacy as aminophylline, the hypersensitivity reactions associated with the latter could be avoided.

Full text

PDF
87

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Antal E. J., Kramer P. A., Mercik S. A., Chapron D. J., Lawson I. R. Theophylline pharmacokinetics in advanced age. Br J Clin Pharmacol. 1981 Nov;12(5):637–645. doi: 10.1111/j.1365-2125.1981.tb01282.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Booth B. H., Coleman W. P., Mitchell D. Q. Urticaria following intravenous aminophylline. Ann Allergy. 1979 Nov;43(5):289–290. [PubMed] [Google Scholar]
  3. Rudzki E., Kleniewska D. The epidemiology of contact dermatitis in Poland. Br J Dermatol. 1970 Nov;83(5):543–545. doi: 10.1111/j.1365-2133.1970.tb15738.x. [DOI] [PubMed] [Google Scholar]
  4. White M. I., Douglas W. S., Main R. A. Contact dermatitis attributed to ethylenediamine. Br Med J. 1978 Feb 18;1(6110):415–416. doi: 10.1136/bmj.1.6110.415. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Wong D., Lopapa A. F., Haddad Z. H. Immediate hypersensitivity reaction to aminophylline. Report of a case with immunologic confirmation by an in vitro procedure. J Allergy Clin Immunol. 1971 Sep;48(3):165–170. doi: 10.1016/0091-6749(71)90012-1. [DOI] [PubMed] [Google Scholar]

Articles from Postgraduate Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES