Abstract
We report the case of a young man with Fusobacterium necrophorum meningitis who developed bilateral carotid artery stenosis associated with thrombosis of the cavernous sinuses. Intraluminal clot was present in the region of the stenoses for which he was anticoagulated. The clinical presentation, problems with diagnosis, the use of anticoagulation and the need for prolonged treatment with metronidazole are discussed.
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- Adams J., Capistrant T., Crossley K., Johanssen R., Liston S. Fusobacterium necrophorum septicemia. JAMA. 1983 Jul 1;250(1):35–35. [PubMed] [Google Scholar]
- Clifford-Jones R. E., Ellis C. J., Stevens J. M., Turner A. Cavernous sinus thrombosis. J Neurol Neurosurg Psychiatry. 1982 Dec;45(12):1092–1097. doi: 10.1136/jnnp.45.12.1092. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Islam A. K., Shneerson J. M. Primary meningitis caused by Bacteroides fragilis and Fusobacterium necrophorum. Postgrad Med J. 1980 May;56(655):351–353. doi: 10.1136/pgmj.56.655.351. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Levine S. R., Twyman R. E., Gilman S. The role of anticoagulation in cavernous sinus thrombosis. Neurology. 1988 Apr;38(4):517–522. doi: 10.1212/wnl.38.4.517. [DOI] [PubMed] [Google Scholar]
- Mitre R. J., Rotheran E. B., Jr Anaerobic septicemia from thrombophlebitis of the internal jugular vein. Successful treatment with metronidazole. JAMA. 1974 Nov 25;230(8):1168–1169. [PubMed] [Google Scholar]
- O'Grady L. R., Ralph E. D. Anaerobic meningitis and bacteremia caused by Fusobacterium species. Am J Dis Child. 1976 Aug;130(8):871–873. doi: 10.1001/archpedi.1976.02120090081015. [DOI] [PubMed] [Google Scholar]
- Parsons M. Intracranial venous thrombosis. Postgrad Med J. 1967 Jun;43(500):409–414. doi: 10.1136/pgmj.43.500.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Seidenfeld S. M., Sutker W. L., Luby J. P. Fusobacterium necrophorum septicemia following oropharyngeal infection. JAMA. 1982 Sep 17;248(11):1348–1350. [PubMed] [Google Scholar]
- Sekhar L. N., Dujovny M., Rao G. R. Carotid-cavernous sinus thrombosis caused by Aspergillus fumigatus. Case report. J Neurosurg. 1980 Jan;52(1):120–125. doi: 10.3171/jns.1980.52.1.0120. [DOI] [PubMed] [Google Scholar]
- TAYLOR P. J. Cavernous sinus thrombophlebitis. Br J Ophthalmol. 1957 Apr;41(4):228–237. doi: 10.1136/bjo.41.4.228. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tärnvik A. Anaerobic meningitis in children. Eur J Clin Microbiol. 1986 Jun;5(3):271–274. doi: 10.1007/BF02017779. [DOI] [PubMed] [Google Scholar]
- Vogel L. C., Boyer K. M. Metastatic complications of Fusobacterium necrophorum sepsis. Two cases of Lemierre's postanginal septicemia. Am J Dis Child. 1980 Apr;134(4):356–358. doi: 10.1001/archpedi.1980.04490010014005. [DOI] [PubMed] [Google Scholar]