Abstract
This study confirms that repeated tuberculin testing may prevent waning of, or restore, tuberculin sensitivity in BCG-vaccinated schoolchildren, and demonstrates that tuberculin testing has this effect even if it is done relatively shortly after vaccination. Therefore the results of repeated tuberculin tests cannot reveal a possible waning of BCG-induced tuberculin sensitivity. This finding shows that a revaccination policy based on the waning of tuberculin sensitivity is not rational.
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- ARONSON J. D., ARONSON C. F., TAYLOR H. C. A twenty-year appraisal of BCG vaccination in the control of tuberculosis. AMA Arch Intern Med. 1958 May;101(5):881–893. doi: 10.1001/archinte.1958.00260170037006. [DOI] [PubMed] [Google Scholar]
- Guld J., Waaler H., Sundaresan T. K., Kaufmann P. C., ten Dam H. G. The duration of BCG-induced tuberculin sensitivity in children, and its irrelevance for revaccination. Results of two 5-year prospective studies. Bull World Health Organ. 1968;39(5):829–836. [PMC free article] [PubMed] [Google Scholar]
- Juchniewicz M., Rudnik J., Olakowski T., Anusz Z., Herman S., Iwanowa O., Mardoń K., Ogarek-Sliwa E. Kontrolowane badania wartości róznych tuberkulin PPD i szczepionek BCG z podszczepu brazylijskiego i francuskiego. IV. Wystepowanie alergii poszczepiennej po 12 miesiacach od zaszczepienia. Gruzlica. 1968 Feb;36(2):117–128. [PubMed] [Google Scholar]
- MAGNUS K., EDWARDS L. B. The effect of repeated tuberculin testing on post-vaccination allergy; a preliminary note. Lancet. 1955 Sep 24;269(6891):643–644. doi: 10.1016/s0140-6736(55)92482-x. [DOI] [PubMed] [Google Scholar]
- Narain R., Nair S. S., Rao G. R., Chandrasekhar P., Lal P. Enhancing of tuberculin allergy by previous tuberculin testing. Bull World Health Organ. 1966;34(4):623–638. [PMC free article] [PubMed] [Google Scholar]
- Tolderlund K., Bentzon M. W., Bunch-Christensen K., Mackeprang B., Guld J., Waaler H. BCG-induced allergy and immunity in guinea-pigs during the first year after vaccination. Bull World Health Organ. 1967;36(5):747–758. [PMC free article] [PubMed] [Google Scholar]
- Tolderlund K., Bunch-Christensen K., Guld J. Duration of allergy and immunity in BCG-vaccinated guinea pigs. A five-year study. Bull World Health Organ. 1967;36(5):759–769. [PMC free article] [PubMed] [Google Scholar]