Abstract
Growing cells of Fusarium oxysporum f.sp. vasinfectum (ATCC 7808) formed 3-acetoxyscirpene-4,15-diol from anguidine (4,15-diacetoxyscirpene-3-ol) by way of the intermediates triacetoxyscirpene, 3,4-diacetoxyscirpene-15-ol and 3,15-diacetoxyscirpene-4-ol. The new 3-acetoxy analog was found to be less active than anguidine and the other monoacetoxy derivatives when tested against a series of fungal strains and against HeLa cells in vitro.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Claridge C. A., Bradner W. T., Schmitz H. Antitumor activity of 15-acetoxyscirpen-3,4-diol. J Antibiot (Tokyo) 1978 May;31(5):485–486. doi: 10.7164/antibiotics.31.485. [DOI] [PubMed] [Google Scholar]
- Claridge C. A., Schmitz H. Microbial and chemical transformations of some 12,13-epoxytrichothec-9,10-enes. Appl Environ Microbiol. 1978 Jul;36(1):63–67. doi: 10.1128/aem.36.1.63-67.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]