Abstract
The analysis of gel banding patterns of penicillin-binding proteins was used to identify two clinical isolates of a coagulase-negative Staphylococcus species as Staphylococcus caprae, a species originally isolated from goat's milk. One of the isolates was further shown to carry mecA, the structural gene for methicillin resistance.
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- Archer G. L. Molecular epidemiology of multiresistant Staphylococcus epidermidis. J Antimicrob Chemother. 1988 Apr;21 (Suppl 100):133–138. doi: 10.1093/jac/21.suppl_c.133. [DOI] [PubMed] [Google Scholar]
- Canepari P., Varaldo P. E., Fontana R., Satta G. Different staphylococcal species contain various numbers of penicillin-binding proteins ranging from four (Staphylococcus aureus) to only one (Staphylococcus hyicus). J Bacteriol. 1985 Aug;163(2):796–798. doi: 10.1128/jb.163.2.796-798.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chambers H. F. Coagulase-negative staphylococci resistant to beta-lactam antibiotics in vivo produce penicillin-binding protein 2a. Antimicrob Agents Chemother. 1987 Dec;31(12):1919–1924. doi: 10.1128/aac.31.12.1919. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hiramatsu K., Suzuki E., Takayama H., Katayama Y., Yokota T. Role of penicillinase plasmids in the stability of the mecA gene in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 1990 Apr;34(4):600–604. doi: 10.1128/aac.34.4.600. [DOI] [PMC free article] [PubMed] [Google Scholar]
- O'Callaghan C. H., Morris A., Kirby S. M., Shingler A. H. Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother. 1972 Apr;1(4):283–288. doi: 10.1128/aac.1.4.283. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pierre J., Gutmann L., Bornet M., Bergogne-Berezin E., Williamson R. Identification of coagulase-negative staphylococci by electrophoretic profile of total proteins and analysis of penicillin-binding proteins. J Clin Microbiol. 1990 Mar;28(3):443–446. doi: 10.1128/jcm.28.3.443-446.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tesch W., Strässle A., Berger-Bächi B., O'Hara D., Reynolds P., Kayser F. H. Cloning and expression of methicillin resistance from Staphylococcus epidermidis in Staphylococcus carnosus. Antimicrob Agents Chemother. 1988 Oct;32(10):1494–1499. doi: 10.1128/aac.32.10.1494. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ubukata K., Nonoguchi R., Matsuhashi M., Konno M. Expression and inducibility in Staphylococcus aureus of the mecA gene, which encodes a methicillin-resistant S. aureus-specific penicillin-binding protein. J Bacteriol. 1989 May;171(5):2882–2885. doi: 10.1128/jb.171.5.2882-2885.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ubukata K., Nonoguchi R., Song M. D., Matsuhashi M., Konno M. Homology of mecA gene in methicillin-resistant Staphylococcus haemolyticus and Staphylococcus simulans to that of Staphylococcus aureus. Antimicrob Agents Chemother. 1990 Jan;34(1):170–172. doi: 10.1128/aac.34.1.170. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Utsui Y., Ohya S., Magaribuchi T., Tajima M., Yokota T. Antibacterial activity of cefmetazole alone and in combination with fosfomycin against methicillin- and cephem-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 1986 Dec;30(6):917–922. doi: 10.1128/aac.30.6.917. [DOI] [PMC free article] [PubMed] [Google Scholar]