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. 1992 Oct;36(10):2342–2345. doi: 10.1128/aac.36.10.2342

Bactericidal activity of ramoplanin against antibiotic-resistant enterococci.

C C Johnson 1, S Taylor 1, P Pitsakis 1, P May 1, M E Levison 1
PMCID: PMC245501  PMID: 1444316

Abstract

Ramoplanin, a new lipoglycodepsipeptide antibiotic, was uniformly active against 65 strains of enterococci, including strains highly resistant to vancomycin, penicillin G, and gentamicin. MBCs were usually within a fourfold dilution of the MICs. In time-kill studies, ramoplanin alone demonstrated dose-dependent bactericidal activity against enterococcal strains that resisted killing by vancomycin or penicillin in combination with gentamicin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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