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. 1974 Aug;119(2):461–468. doi: 10.1128/jb.119.2.461-468.1974

Clustering of the Genes for Allantoin Degradation in Saccharomyces cerevisiae

Robert P Lawther 1, Elaine Riemer 1, Bonnie Chojnacki 1, Terrance G Cooper 1
PMCID: PMC245628  PMID: 4604238

Abstract

We have shown that allantoin degradation in Saccharomyces cerevisiae proceeds exclusively through the intermediate formation of allantoic acid, urea, and allophanic acid. The number of reactions between allantoic acid and urea, however, remains obscure owing to our inability to isolate a mutant defective in ureidoglycolate hydrolase. Structural genes for the enzymes, allantoinase (dal1) and allantoicase (dal2) are located on chromosome IX promixal to the centromere in the order dal1-dal2-lysl.

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Selected References

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