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. 1973 Sep;115(3):727–731. doi: 10.1128/jb.115.3.727-731.1973

Accumulation of Methylglyoxal in a Mutant of Escherichia coli Constitutive for Gluconate Catabolism

U D Rekarte a, N Zwaig a,1, T Istúriz a,2
PMCID: PMC246314  PMID: 4580565

Abstract

A culture of a mutant of Escherichia coli, derepressed for gluconate catabolism, is killed by the addition of gluconate to the culture. The product responsible for this bactericidal effect was identified as methylglyoxal. Two types of mutants resistant to gluconate were isolated. One of them showed increased activity of glyoxalase I.

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Selected References

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