Abstract
A new subtype of avian influenzavirus A was isolated in January 1967 from an epizootic in a turkey hatchery in Ontario, Canada. The disease was fatal in 65 of 2 500 hens involved. Virus was isolated from lung and trachea tissue of three dead turkeys. Sera from convalescent birds contained antibody against the viruses isolated from the outbreak but not against other known type A avian influenzaviruses, Newcastle disease virus, Myxovirus Yucaipa, or Mycoplasma gallisepticum.
The strain designated A/turkey/Ontario/6118/67 contained the influenza A type ribonucleoprotein. Haemagglutinin and neuraminidase antigens of the strain differed antigenically from the envelope antigens of other avian influenzaviruses isolated from birds, horses, pigs, or man. The designation of turkey/Ontario/6118/67 as containing haemagglutinin of avian subtype 8 (Hav 8) and neuraminidase of avian subtype 4 (Nav 4) is proposed.
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Selected References
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- Beard C. W. Avian influenza antibody detection by immunodiffusion. Avian Dis. 1970 May;14(2):337–341. [PubMed] [Google Scholar]
- LIEF F. S., FABIYI A., HENLE W. Antigenic analyses of influenza viruses by complement fixation. I. The production of antibodies to the soluble antigen in guinea pigs. J Immunol. 1958 Jan;80(1):53–65. [PubMed] [Google Scholar]
- Pereira H. G. Antigenic variation in influenza viruses in man and animals. Proc R Soc Med. 1969 Jan;62(1):43–44. [PMC free article] [PubMed] [Google Scholar]
- Pereira H. G., Lang G., Olesiuk O. M., Snoeyenbos G. H., Roberts D. H., Easterday B. C. New antigenic variants of avian influenza A viruses. Bull World Health Organ. 1966;35(5):799–802. [PMC free article] [PubMed] [Google Scholar]
- Schild G. C., Newman R. W. Immunological relationships between the neuraminidases of human and animal influenza viruses. Bull World Health Organ. 1969;41(3):437–445. [PMC free article] [PubMed] [Google Scholar]
- Schild G. C., Pereira H. G., Schettler C. H. Neuraminidase in avin influenza A virus antigenically related to that of human A0 and A1 subtypes. Nature. 1969 Jun 28;222(5200):1299–1301. doi: 10.1038/2221299a0. [DOI] [PubMed] [Google Scholar]
- Tumova B., Easterday B. C. Relationship of envelope antigens of animal influenza viruses to human A2 influenza strains isolated in the years 1957-68. Bull World Health Organ. 1969;41(3):429–435. [PMC free article] [PubMed] [Google Scholar]
- Tůmová B., Pereira H. G. Antigenic relationship between influenza A viruses of human and animal origin. Bull World Health Organ. 1968;38(3):415–420. [PMC free article] [PubMed] [Google Scholar]
- Webster R. G., Pereira H. G. A common surface antigen in influenza viruses from human and avian sources. J Gen Virol. 1968 Sep;3(2):201–208. doi: 10.1099/0022-1317-3-2-201. [DOI] [PubMed] [Google Scholar]