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. 1971 Jan;105(1):211–219. doi: 10.1128/jb.105.1.211-219.1971

Methylation of the Flagellin of Salmonella typhimurium

Steven R Tronick a,1, Rafael J Martinez a
PMCID: PMC248343  PMID: 5541007

Abstract

The methylation of endogenous proteins by Salmonella typhimurium SL 870 was investigated in cell-free extracts by using S-adenosylmethionine as methyl donor. Several lines of evidence are presented which suggest that one of the methylated products is the protein flagellin. Mutant strains of SL 870 (nml−fla+ and nml+fla−) were also found to synthesize epsilon-N-methyl-lysine. It is proposed that S. typhimurium possesses at least two genes specifying different methylating enzymes. One gene product is a flagellin-specific methylating enzyme, whereas the other gene(s) codes for enzymes that methylate one or more other cell proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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