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Annals of The Royal College of Surgeons of England logoLink to Annals of The Royal College of Surgeons of England
. 1980 Nov;62(6):432–438.

Progress and frustration in inflammatory bowel disease.

B N Brooke
PMCID: PMC2493771  PMID: 7002013

Abstract

Advances -- and lack of them -- in our understanding of the aetiology, nature, and treatment of ulcerative colitis and Crohn's disease during the past 30 years are reviewed with special reference to personal experience.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AYLETT S. O. Conservative surgery in the treatment of ulcerative colitis. Br Med J. 1953 Dec 19;2(4850):1348–1351. doi: 10.1136/bmj.2.4850.1348. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BROOKE B. N., SLANEY G. Portal bacteraemia in ulcerative colitis. Lancet. 1958 Jun 7;1(7032):1206–1207. doi: 10.1016/s0140-6736(58)91910-x. [DOI] [PubMed] [Google Scholar]
  3. BROOKE B. N. The management of an ileostomy, including its complications. Lancet. 1952 Jul 19;2(6725):102–104. doi: 10.1016/s0140-6736(52)92149-1. [DOI] [PubMed] [Google Scholar]
  4. BROOKE B. N. The surgery of ulcerative colitis. Ann R Coll Surg Engl. 1951 Jun;8(6):440–456. [PMC free article] [PubMed] [Google Scholar]
  5. BROOKE B. N. Total colectomy in one stage for ulcerative colitis. Lancet. 1951 Jun 2;1(6666):1197–1199. doi: 10.1016/s0140-6736(51)92705-5. [DOI] [PubMed] [Google Scholar]
  6. BROOKE B. N. What is ulcerative colitis? Lancet. 1953 Jun 20;1(6773):1220–1225. doi: 10.1016/s0140-6736(53)92256-9. [DOI] [PubMed] [Google Scholar]
  7. Beeken W. L., Mitchell D. N., Cave D. R. Evidence for a transmissible agent in Crohn's disease. Clin Gastroenterol. 1976 May;5(2):289–302. [PubMed] [Google Scholar]
  8. Blichfeldt P., Blomhoff J. P., Myhre E., Gjone E. Metronidazole in Crohn's disease. A double blind cross-over clinical trial. Scand J Gastroenterol. 1978;13(1):123–127. doi: 10.3109/00365527809179816. [DOI] [PubMed] [Google Scholar]
  9. Bolton R. P., Sherriff R. J., Read A. E. Clostridium difficile associated diarrhoea: a role in inflammatory bowel disease? Lancet. 1980 Feb 23;1(8165):383–384. doi: 10.1016/s0140-6736(80)90940-x. [DOI] [PubMed] [Google Scholar]
  10. Brooke B. N., Hoffmann D. C., Swarbrick E. T. Azathioprine for Crohn's disease. Lancet. 1969 Sep 20;2(7621):612–614. doi: 10.1016/s0140-6736(69)90325-0. [DOI] [PubMed] [Google Scholar]
  11. Burnham W. R., Lennard-Jones J. E., Stanford J. L., Bird R. G. Mycobacteria as a possible cause of inflammatory bowel disease. Lancet. 1978 Sep 30;2(8092 Pt 1):693–696. doi: 10.1016/s0140-6736(78)92699-5. [DOI] [PubMed] [Google Scholar]
  12. Cave D. R., Mitchell D. N., Kane S. P., Brooke B. N. Further animal evidence of a transmissible agent in Crohn's disease. Lancet. 1973 Nov 17;2(7838):1120–1122. doi: 10.1016/s0140-6736(73)90936-7. [DOI] [PubMed] [Google Scholar]
  13. Davies P. S., Rhodes J., Heatley R. V., Owen E. Metronidazole in the treatment of chronic proctitis: a controlled trial. Gut. 1977 Aug;18(8):680–681. doi: 10.1136/gut.18.8.680. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. De Dombal F. T. Results of surgical treatment for Crohn's disease. Br J Surg. 1972 Oct;59(10):826–829. doi: 10.1002/bjs.1800591022. [DOI] [PubMed] [Google Scholar]
  15. Floch H. F., Slattery L. R., Hazzi C. G. Carcinoma of the small intestine in regional enteritis: presentation of a case and review of the literature. Am J Gastroenterol. 1978 Nov;70(5):520–527. [PubMed] [Google Scholar]
  16. Gitnick G. L., Rosen V. J. Electron microscopic studies of viral agents in Crohn's disease. Lancet. 1976 Jul 31;2(7979):217–219. doi: 10.1016/s0140-6736(76)91023-0. [DOI] [PubMed] [Google Scholar]
  17. Greenstein A. J., Sachar D. B., Smith H., Pucillo A., Papatestas A. E., Kreel I., Geller S. A., Janowitz H. D., Aufses A. H., Jr Cancer in universal and left-sided ulcerative colitis: factors determining risk. Gastroenterology. 1979 Aug;77(2):290–294. [PubMed] [Google Scholar]
  18. Kewenter J., Ahlman H., Hultén L. Cancer risk in extensive ulcerative colitis. Ann Surg. 1978 Dec;188(6):824–828. doi: 10.1097/00000658-197812000-00018. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. LaMont J. T., Trnka Y. M. Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease. Lancet. 1980 Feb 23;1(8165):381–383. doi: 10.1016/s0140-6736(80)90939-3. [DOI] [PubMed] [Google Scholar]
  20. Morson B. C., Pang L. S. Rectal biopsy as an aid to cancer control in ulcerative colitis. Gut. 1967 Oct;8(5):423–434. doi: 10.1136/gut.8.5.423. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Parent K., Mitchell P. Cell wall-defective variants of pseudomonas-like (group Va) bacteria in Crohn's disease. Gastroenterology. 1978 Sep;75(3):368–372. [PubMed] [Google Scholar]
  22. Persson S., Danielsson D., Kjellander J., Wallensten S. Studies on Crohn's disease. 1. The relationship between Yersinia enterocolitica infection and terminal ileitis. Acta Chir Scand. 1976;142(1):84–90. [PubMed] [Google Scholar]
  23. Phillpotts R. J., Hermon-Taylor J., Brooke B. N. Virus isolation studies in Crohn's disease: a negative report. Gut. 1979 Dec;20(12):1057–1062. doi: 10.1136/gut.20.12.1057. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Ritchie J. K. Results of surgery for inflammatory bowel disease: a further survey of one hospital region. Br Med J. 1974 Feb 16;1(5902):264–268. doi: 10.1136/bmj.1.5902.264. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. SAMPSON P. A., BROOKE B. N., WINSTONE N. E. Biochemical confirmation of collapse due to adrenal failure. Lancet. 1961 Jun 24;1(7191):1377–1377. doi: 10.1016/s0140-6736(61)92007-4. [DOI] [PubMed] [Google Scholar]
  26. SAMPSON P. A., WALKER F. C. Dilatation of the colon in ulcerative colitis. Br Med J. 1961 Oct 28;2(5260):1119–1132. doi: 10.1136/bmj.2.5260.1119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. SAMPSON P. A., WINSTONE N. E., BROOKE B. N. Adrenal function in surgical patients after steroid therapy. Lancet. 1962 Aug 18;2(7251):322–325. doi: 10.1016/s0140-6736(62)90108-3. [DOI] [PubMed] [Google Scholar]
  28. SLANEY G., BROOKE B. N. Cancer in ulcerative colitis. Lancet. 1959 Oct 31;2(7105):694–698. doi: 10.1016/s0140-6736(59)92130-0. [DOI] [PubMed] [Google Scholar]
  29. Stanford J. L., White S. A., Burnham W. R., Lennard-Jones J. E., Bird R. G. Mycobacteria and inflammatory bowel disease. Lancet. 1979 Feb 24;1(8113):444–444. doi: 10.1016/s0140-6736(79)90922-x. [DOI] [PubMed] [Google Scholar]
  30. Storgaard L., Bischoff N., Henriksen F. W., Fischerman K., Jarnum S. Survival rate in Crohn's disease and ulcerative colitis. Scand J Gastroenterol. 1979;14(2):225–230. doi: 10.3109/00365527909179874. [DOI] [PubMed] [Google Scholar]
  31. Valdes-Dapena A., Rudolph I., Hidayat A., Roth J. L., Laucks R. B. Adenocarcinoma of the small bowel in association with regional enteritis. Four new cases. Cancer. 1976 Jun;37(6):2938–2947. doi: 10.1002/1097-0142(197606)37:6<2938::aid-cncr2820370651>3.0.co;2-o. [DOI] [PubMed] [Google Scholar]
  32. WARREN R., McKITTRICK L. S. Ileostomy for ulcerative colitis; technique, complications, and management. Surg Gynecol Obstet. 1951 Nov;93(5):555–567. [PubMed] [Google Scholar]
  33. Wyatt A. P. Regional enteritis leading to carcinoma of the small bowel. Gut. 1969 Nov;10(11):924–927. doi: 10.1136/gut.10.11.924. [DOI] [PMC free article] [PubMed] [Google Scholar]

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