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. 1991 Nov;73(6):361–363.

ERICA predicts response to tamoxifen in elderly women with breast cancer.

N Davies 1, G Moir 1, R Carpenter 1, A Cuthbert 1, A Herbert 1, G T Royle 1, I Taylor 1
PMCID: PMC2499444  PMID: 1759765

Abstract

Oestrogen receptor status has been determined by an immunocytochemical assay using fine-needle aspiration samples of primary breast cancers in elderly patients. In a prospective study 56 patients were treated with tamoxifen only. Satisfactory assays were achieved in 49 patients. Disease was controlled by tamoxifen in 32 of 35 (91%) patients with oestrogen receptor positive tumours, compared with only 1 (7%) of 14 who were receptor negative. Immunocytochemical assay on fine-needle aspiration samples is relatively non-invasive and simple to perform, it accurately predicts response to tamoxifen in elderly patients and can be used to select patients for tamoxifen only therapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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