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. 1969 Sep;99(3):707–712. doi: 10.1128/jb.99.3.707-712.1969

Regulation of 3-Deoxy-d-arabino-Heptulosonic 7-Phosphate Acid Synthetase Activity in Relation to the Synthesis of the Aromatic Vitamins in Escherichia coli K-12

B J Wallace 1, J Pittard 1
PMCID: PMC250085  PMID: 4905534

Abstract

Both in vivo and in vitro experiments on wild-type Escherichia coli K-12 and mutant strains possessing only single 3-deoxy-d-arabino-heptulosonic 7-phosphate acid (DAHP) synthetase isoenzymes indicated that, under conditions when all three isoenzymes are fully repressed, sufficient chorismate is still formed for the synthesis of aromatic vitamins. Under repressed conditions both DAHP synthetase (phe) and (trp), but not DAHP synthetase (tyr), were shown to contribute to vitamin production.

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Selected References

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