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. 1968 Sep;96(3):660–664. doi: 10.1128/jb.96.3.660-664.1968

Lipoidal Components of Bacterial Lipopolysaccharides: Nature and Distribution of Fatty Acids in Aerobacter aerogenes

John I Gallin 1, William M O'Leary 1
PMCID: PMC252356  PMID: 5732501

Abstract

The fatty acid distribution of Aerobacter aerogenes was studied by comparing the fatty acid composition of the lipoidal component of the endotoxin (lipid A) with the fatty acids of the readily extractable native lipids and total cellular fatty acids. The results for total cellular fatty acids and readily extractable native lipids were generally similar, but both quantitative and qualitative differences exist. In addition, profound differences between these two fractions and lipid A were observed. These differences included fewer fatty acids and lower concentrations of unsaturated and cyclopropane fatty acids in the lipid A. Hydroxy fatty acids persisted in the lipid A. The significance of these differences with respect to mammalian toxicity of endotoxins is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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