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. 1968 Oct;96(4):1150–1158. doi: 10.1128/jb.96.4.1150-1158.1968

Effects of Ionizing Radiation on Synchronous Cultures of Escherichia coli B/r

D Joseph Clark a,1
PMCID: PMC252429  PMID: 4879555

Abstract

The sensitivity of Escherichia coli B/r to X-irradiation is correlated with the replication cycle of deoxyribonucleic acid (DNA). The sensitivity to X-irradiation in the wild type can be attributed to the presence of nuclear targets plus DNA repair mechanisms. The effects of nuclear targets are observed in the recombination-deficient (rec−) mutant B/r, but the sensitivity reflected by changes in the slope of killing curves is absent. A study of different growth conditions indicates that maximal resistance to X rays occurs toward the middle of the division cycle. Evidence is offered that branched chromosomes respond as one-hit targets to X-irradiation. The killing effects of heavy-ion bombardment on E. coli are due primarily to ionizing radiation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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