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. 1986 Apr;58(1):179–184. doi: 10.1128/jvi.58.1.179-184.1986

Specific lysis of varicella zoster virus-infected B lymphoblasts by human T cells.

A R Hayward, O Pontesilli, M Herberger, M Laszlo, M Levin
PMCID: PMC252891  PMID: 3005647

Abstract

Epstein-Barr virus-transformed human B cells expressed cell surface varicella-zoster virus (VZV) antigens after superinfection with VZV although they did not form infectious centers in a plaque assay. The VZV-superinfected cells were lysed by autologous VZV-stimulated T-cell lines and their derivative clones. The effector cells were specific for VZV and an HLA DR antigen and were T4+. The specificity of lysis of Epstein-Barr virus-transformed, VZV-superinfected targets by prestimulated mononuclear cells in this system contrasted with the unrestricted lysis seen when the targets were VZV-infected fibroblasts.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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