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. 1988 Dec;62(12):4824–4827. doi: 10.1128/jvi.62.12.4824-4827.1988

A repeat sequence, GGGTTA, is shared by DNA of human herpesvirus 6 and Marek's disease virus.

M Kishi 1, H Harada 1, M Takahashi 1, A Tanaka 1, M Hayashi 1, M Nonoyama 1, S F Josephs 1, A Buchbinder 1, F Schachter 1, D V Ablashi 1, et al.
PMCID: PMC253608  PMID: 2846894

Abstract

Some regions of the genomes of human B-lymphotrophic virus (HBLV), also designated as human herpesvirus 6, and Marek's disease virus were found to hybridize to each other under moderate to stringent conditions, scoring from 10 to 30% base-pair mismatch. Nucleotide sequence analysis showed that a 6-base-pair repetitive sequence, GGGTTA (DR2), present in the IRS-IRL junction region of the Marek's disease virus genome, was also reiterated in the HBLV genome. The function(s) of such a sequence is unknown, but this is the first report of homology between HBLV and a nonhuman herpesvirus.

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Selected References

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