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. 1956;15(3-5):775–784.

Suppression of malaria with pyrimethamine in Nigerian school-children

H Munro Archibald, Leonard J Bruce-Chwatt
PMCID: PMC2538299  PMID: 13404449

Abstract

The authors describe a two-year investigation carried out on a group of Nigerian schoolchildren with the object of assessing the effect of suppressing malaria infection with pyrimethamine on the physical development of the African child. The results showed that the average gain in weight of the treated children over the period of the investigation was significantly greater than that of the untreated children. Despite the relatively high weekly dose of the drug no side-effects were observed, and no alarming manifestation of malaria was noted when administration of the drug was discontinued.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARCHIBALD H. M. Preliminary field trials on a new schizonticide. Br Med J. 1951 Oct 6;2(4735):821–823. doi: 10.1136/bmj.2.4735.821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BRUCE-CHWATT L. J., ARCHIBALD H. M. Field trials of new antimalarials in West Africa. Br Med J. 1953 Mar 7;1(4809):539–541. doi: 10.1136/bmj.1.4809.539. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BRUCE-CHWATT L. J. Malaria in African infants and children in Southern Nigeria. Ann Trop Med Parasitol. 1952 Sep;46(2):173–200. doi: 10.1080/00034983.1952.11685522. [DOI] [PubMed] [Google Scholar]
  4. CLEMENTS E. M. Changes in the mean stature and weight of British children over the past seventy years. Br Med J. 1953 Oct 24;2(4842):897–902. doi: 10.1136/bmj.2.4842.897. [DOI] [PMC free article] [PubMed] [Google Scholar]

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