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. 1988 Jan 23;296(6617):251–254. doi: 10.1136/bmj.296.6617.251

Development of long term use of psychotropic drugs by general practice patients

Andrea Mant, Paul Duncan-Jones, Deborah Saltman, Charles Bridges-Webb, Linda Kehoe, Gwenda Lansbury, Alan H B Chancellor
PMCID: PMC2544775  PMID: 2893650

Abstract

From 1984 to 1986 a prospective study was conducted of 104 general practice patients who started treatment with a benzodiazepine or an antidepressant drug. The duration of reported use of the drugs was two months for 45% of patients, four months for 17% of patients, and six months for 15%. Type of drug, age, and level of education were found to be predictive of continuing use.

General practitioners have a significant effect on their patients' use of drugs and, with careful selection and review when prescribing, may help to prevent dependence on psychotropic drugs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ashton H. Benzodiazepine withdrawal: an unfinished story. Br Med J (Clin Res Ed) 1984 Apr 14;288(6424):1135–1140. doi: 10.1136/bmj.288.6424.1135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bridges-Webb C., Mant A., Britt H. Long-term psychotropic drug prescribing for general practice patients. Fam Pract. 1985 Dec;2(4):238–240. doi: 10.1093/fampra/2.4.238. [DOI] [PubMed] [Google Scholar]
  3. Busto U., Sellers E. M., Naranjo C. A., Cappell H., Sanchez-Craig M., Sykora K. Withdrawal reaction after long-term therapeutic use of benzodiazepines. N Engl J Med. 1986 Oct 2;315(14):854–859. doi: 10.1056/NEJM198610023151403. [DOI] [PubMed] [Google Scholar]
  4. Catalan J., Gath D. H. Benzodiazepines in general practice: time for a decision. Br Med J (Clin Res Ed) 1985 May 11;290(6479):1374–1376. doi: 10.1136/bmj.290.6479.1374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Chancellor A., Mant A., Andrews G. The general practitioner's identification and management of emotional disorders. Aust Fam Physician. 1977 Sep;6(9):1137–1143. [PubMed] [Google Scholar]
  6. Fleming D. M., Cross K. W. Psychotropic drug prescribing. J R Coll Gen Pract. 1984 Apr;34(261):216–220. [PMC free article] [PubMed] [Google Scholar]
  7. Hesbacher P., Rickels K., Rial W. Y., Segal A., Zamostien B. B. Psychotropic drug prescription in family practice. Compr Psychiatry. 1976 Sep-Oct;17(5):607–615. doi: 10.1016/s0010-440x(76)80004-1. [DOI] [PubMed] [Google Scholar]
  8. Jones L., Simpson D., Brown A. C., Bainton D., McDonald H. Prescribing psychotropic drugs in general practice: three year study. Br Med J (Clin Res Ed) 1984 Oct 20;289(6451):1045–1048. doi: 10.1136/bmj.289.6451.1045. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Lader M. A practical guide to prescribing hypnotic benzodiazepines. Br Med J (Clin Res Ed) 1986 Oct 25;293(6554):1048–1049. doi: 10.1136/bmj.293.6554.1048. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Lee E. T., Desu M. M. A computer program for comparing K samples with right-censored data. Comput Programs Biomed. 1972 Nov;2(4):315–321. doi: 10.1016/0010-468x(72)90019-0. [DOI] [PubMed] [Google Scholar]
  11. Mant A., Broom D. H., Duncan-Jones P. The path to prescription: sex differences in psychotropic drug prescribing for general practice patients. Soc Psychiatry. 1983;18(4):185–192. doi: 10.1007/BF00583529. [DOI] [PubMed] [Google Scholar]
  12. Mant A., Lansbury G., Bridges-Webb C. A survey of new users of psychotropic drugs in Australian general practice. Fam Pract. 1987 Mar;4(1):50–55. doi: 10.1093/fampra/4.1.50. [DOI] [PubMed] [Google Scholar]
  13. Mellinger G. D., Balter M. B., Uhlenhuth E. H. Insomnia and its treatment. Prevalence and correlates. Arch Gen Psychiatry. 1985 Mar;42(3):225–232. doi: 10.1001/archpsyc.1985.01790260019002. [DOI] [PubMed] [Google Scholar]
  14. Mellinger G. D., Balter M. B., Uhlenhuth E. H. Prevalence and correlates of the long-term regular use of anxiolytics. JAMA. 1984 Jan 20;251(3):375–379. [PubMed] [Google Scholar]
  15. Morgan H. G. Do minor affective disorders need medication? Br Med J (Clin Res Ed) 1984 Sep 29;289(6448):783–783. doi: 10.1136/bmj.289.6448.783. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Petursson H., Lader M. H. Withdrawal from long-term benzodiazepine treatment. Br Med J (Clin Res Ed) 1981 Sep 5;283(6292):643–645. doi: 10.1136/bmj.283.6292.643. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Richardson J. W., 3rd, Richelson E. Antidepressants: a clinical update for medical practitioners. Mayo Clin Proc. 1984 May;59(5):330–337. doi: 10.1016/s0025-6196(12)61429-3. [DOI] [PubMed] [Google Scholar]
  18. Rickels K., Case W. G., Schweizer E. E., Swenson C., Fridman R. B. Low-dose dependence in chronic benzodiazepine users: a preliminary report on 119 patients. Psychopharmacol Bull. 1986;22(2):407–415. [PubMed] [Google Scholar]
  19. Skegg D. C., Doll R., Perry J. Use of medicines in general practice. Br Med J. 1977 Jun 18;1(6076):1561–1563. doi: 10.1136/bmj.1.6076.1561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Tyrer P., Owen R., Dawling S. Gradual withdrawal of diazepam after long-term therapy. Lancet. 1983 Jun 25;1(8339):1402–1406. doi: 10.1016/s0140-6736(83)92355-3. [DOI] [PubMed] [Google Scholar]
  21. Wells K. B., Kamberg C., Brook R., Camp P., Rogers W. Health status, sociodemographic factors, and the use of prescribed psychotropic drugs. Med Care. 1985 Nov;23(11):1295–1306. doi: 10.1097/00005650-198511000-00008. [DOI] [PubMed] [Google Scholar]
  22. Williams P. Factor influencing the duration of treatment with psychotropic drugs in general practice: a survival analysis approach. Psychol Med. 1983 Aug;13(3):623–633. doi: 10.1017/s0033291700048030. [DOI] [PubMed] [Google Scholar]

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