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letter
. 1981 Nov;73(11):1047–1054.

Advanced Skin Cancer in Tanzanian Albinos: Preliminary Observations

George A Alexander, Ulrich K Henschke
PMCID: PMC2552804  PMID: 7310920

Abstract

Ten cases of advanced squamous cell carcinoma of the skin in albinos, treated by radiotherapy from 1973 to 1979 at the Muhimbili Medical Center of Dar-es-Salaam, have been reviewed. Age, sex, duration of symptoms, anatomic distribution, stage of disease, and treatment are reviewed. The relationship between albinism, sunlight, and skin cancer is discussed and a practical program of prevention is suggested. Advanced carcinoma of skin in albinos may be managed successfully with judicious radiation therapy. Excellent objective responses have been noted. No assessment of long-term control is made due to poor follow-up of patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson C. Malignancies in mainland Tanzania: squamous cell carcinomas. Acta Trop. 1970;27(3):208–218. [PubMed] [Google Scholar]
  2. BARNICOT N. A. Albinism in south-western Nigeria. Ann Eugen. 1952 Aug;17(Pt 1):38–73. doi: 10.1111/j.1469-1809.1953.tb02535.x. [DOI] [PubMed] [Google Scholar]
  3. Jelliffe D. B., Jelliffe E. F. Albinism among the San Blas Indians. Lancet. 1972 Feb 26;1(7748):487–488. doi: 10.1016/s0140-6736(72)90139-0. [DOI] [PubMed] [Google Scholar]
  4. KENNEDY B. J., ZELICKSON A. S. MELANOMA IN AN ALBINO. JAMA. 1963 Nov 30;186:839–841. doi: 10.1001/jama.1963.03710090039008. [DOI] [PubMed] [Google Scholar]
  5. KUGELMAN T. P., VAN SCOTT E. J. Tyrosinase activity in melanocytes of human albinos. J Invest Dermatol. 1961 Jul;37:73–76. [PubMed] [Google Scholar]
  6. Kaminester L. H. Sunlight, skin cancer, and suncreens. JAMA. 1975 Jun 30;232(13):1373–1374. [PubMed] [Google Scholar]
  7. Keeler C. Cuna Moon-child albinism, 1950-1970. J Hered. 1970 Nov-Dec;61(6):273–278. doi: 10.1093/oxfordjournals.jhered.a108100. [DOI] [PubMed] [Google Scholar]
  8. Okoro A. N. Albinism in Nigeria. A clinical and social study. Br J Dermatol. 1975 May;92(5):485–492. [PubMed] [Google Scholar]
  9. SHAPIRO M. P., KEEN P., COHEN L., MURRAY J. F. Skin cancer in the South African Bantu. Br J Cancer. 1953 Mar;7(1):45–57. doi: 10.1038/bjc.1953.5. [DOI] [PMC free article] [PubMed] [Google Scholar]

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