Abstract
In his review of pathological studies on Japanese encephalitis conducted in Japan over the past 40 years, the author first discusses the findings obtained from post-mortem examinations of persons who had died of the disease, and, secondly, summarizes experimental research carried out on monkeys, horses and mice. He stresses that, although a great deal has been learned from these studies, much research is still needed, in which modern laboratory techniques give good hopes of success.
This review suggests that before the Second World War the histopathological findings in Japanese encephalitis resembled those of eastern equine encephalitis but that since the war they have been more like those of western equine encephalitis, although no definitive explanation of this phenomenon can yet be offered.