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. 1964;30(5):653–662.

Serological responses of man to typhoid vaccines

A S Benenson
PMCID: PMC2554993  PMID: 14196813

Abstract

Study of the serological responses in man to typhoid vaccines tested in several WHO-sponsored controlled field trials in British Guiana, Poland and Yugoslavia has not indicated any correlation between the level of Vi and O antibodies elicited and the effectiveness of the vaccines. Instead, the more effective vaccines have elicited significantly greater H-antibody responses; but a variety of factors suggests that it may in fact not be the antibody that confers immunity to the disease. The phagocytic test does not appear promising as a technique for determining the effectiveness of a typhoid vaccine, but passive protection of the chick-embryo may warrant further investigation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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