Abstract
Mass vaccination of the juvenile population with live poliovirus vaccine was carried out in Poland in 1959 and 1960. In all, some 7 239 000 children 6 months to 14 years old were given type 1 (CHAT) virus, and nearly 6 818 500 children of the same age-group received type 3 (W-Fox) virus.
A serological conversion rate (from <1:4 to ≥1:4) of 91.7% was achieved with type 1 and of 91.0% with type 3—a satisfactory demonstration of the immunogenicity of the strains used. Although type 2 virus was not administered, seroconversion with this type occurred in 65.4%. This may have been caused by antigenic elements common to the three poliovirus types, and previous vaccination with Salk vaccine may also have been a contributory factor.
The authors conclude that the mass vaccination described in this paper has created a highly immune population in Poland.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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