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. 1983 Mar;45(3):1147–1149. doi: 10.1128/jvi.45.3.1147-1149.1983

The ocr+ Gene Function of Bacteriophages T3 and T7 Counteracts the Salmonella typhimurium DNA Restriction Systems SA and SB

Detlev H Krüger 1, Sigrid Hansen 1, Monika Reuter 1
PMCID: PMC256523  PMID: 6300450

Abstract

In host cells containing the Salmonella typhimurium DNA restriction-modification systems SA+ and SB+, replication of the ocr+ bacteriophages T3 and T7 is not impaired. However, ocr (gene 0.3) mutants of these phages are susceptible to DNA restriction and modification by the SA+ and SB+ systems.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bailey J. N., Dembinski D. R., McAllister W. T. Derivation of a restriction map of bacteriophage T3 DNA and comparison with the map of bacteriophage T7 DNA. J Virol. 1980 Jul;35(1):176–183. doi: 10.1128/jvi.35.1.176-183.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brunovskis I., Burns R. O. Growth of coliphage T7 in Salmonella typhimurium. J Virol. 1973 May;11(5):621–629. doi: 10.1128/jvi.11.5.621-629.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bullas L. R., Colson C., Neufeld B. Deoxyribonucleic acid restriction and modification systems in Salmonella: chromosomally located systems of different serotypes. J Bacteriol. 1980 Jan;141(1):275–292. doi: 10.1128/jb.141.1.275-292.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Colson C., Van Pel A. DNA restriction and modification systems in Salmonella. I. SA and SB, two Salmonella typhimurium systems determined by genes with a chromosomal location comparable to that of the Escherichia coli hsd genes. Mol Gen Genet. 1974 Apr 3;129(4):325–337. doi: 10.1007/BF00265696. [DOI] [PubMed] [Google Scholar]
  5. Gómez-Eichelmann M. C. Deoxyribonucleic acid adenine and cytosine methylation in Salmonella typhimurium and Salmonella typhi. J Bacteriol. 1979 Nov;140(2):574–579. doi: 10.1128/jb.140.2.574-579.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hattman S., Schlagman S., Goldstein L., Frohlich M. Salmonella typhimurium SA host specificity system is based on deoxyribonucleic acid-adenine methylation. J Bacteriol. 1976 Jul;127(1):211–217. doi: 10.1128/jb.127.1.211-217.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Krüger D. H., Reuter M., Hansen S., Schroeder C. Influence of phage T3 and T7 gene functions on a type III(EcoP1) DNA restriction-modification system in vivo. Mol Gen Genet. 1982;185(3):457–461. doi: 10.1007/BF00334140. [DOI] [PubMed] [Google Scholar]
  8. Krüger D. H., Schroeder C. Bacteriophage T3 and bacteriophage T7 virus-host cell interactions. Microbiol Rev. 1981 Mar;45(1):9–51. doi: 10.1128/mr.45.1.9-51.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Krüger D. H., Schroeder C., Hansen S., Rosenthal H. A. Active protection by bacteriophages T3 and T7 against E. coli B- and K-specific restriction of their DNA. Mol Gen Genet. 1977 May 20;153(1):99–106. doi: 10.1007/BF01036001. [DOI] [PubMed] [Google Scholar]
  10. Studier F. W. Gene 0.3 of bacteriophage T7 acts to overcome the DNA restriction system of the host. J Mol Biol. 1975 May 15;94(2):283–295. doi: 10.1016/0022-2836(75)90083-2. [DOI] [PubMed] [Google Scholar]
  11. Van Pel A., Colson C. DNA restriction and modification systems in Salmonella. II. Genetic complementation between the K and B systems of Escherichia coli and the Salmonella typhimurium system SB, with the same chromosomal location. Mol Gen Genet. 1974;135(1):51–60. doi: 10.1007/BF00433901. [DOI] [PubMed] [Google Scholar]

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