Abstract
Mice passively immunized prior to a challenge infection with immunoglobulin G (IgG) and IgM monoclonal antibodies (MAbs) specific for a common epitope of both A- and M-dominant strains had viable Brucella abortus 544 or Brucella melitensis H38 counts in the spleen reduced to the same extent as did mice passively immunized with MAbs specific for either the A or the M epitope. The IgA MAb was not effective.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bundle D. R., Cherwonogrodzky J. W., Gidney M. A., Meikle P. J., Perry M. B., Peters T. Definition of Brucella A and M epitopes by monoclonal typing reagents and synthetic oligosaccharides. Infect Immun. 1989 Sep;57(9):2829–2836. doi: 10.1128/iai.57.9.2829-2836.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bundle D. R., Cherwonogrodzky J. W., Perry M. B. The structure of the lipopolysaccharide O-chain (M antigen) and polysaccharide B produced by Brucella melitensis 16M. FEBS Lett. 1987 Jun 1;216(2):261–264. doi: 10.1016/0014-5793(87)80702-0. [DOI] [PubMed] [Google Scholar]
- Cloeckaert A., de Wergifosse P., Dubray G., Limet J. N. Identification of seven surface-exposed Brucella outer membrane proteins by use of monoclonal antibodies: immunogold labeling for electron microscopy and enzyme-linked immunosorbent assay. Infect Immun. 1990 Dec;58(12):3980–3987. doi: 10.1128/iai.58.12.3980-3987.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Douglas J. T., Palmer D. A. Use of monoclonal antibodies to identify the distribution of A and M epitopes on smooth Brucella species. J Clin Microbiol. 1988 Jul;26(7):1353–1356. doi: 10.1128/jcm.26.7.1353-1356.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Garin-Bastuji B., Bowden R. A., Dubray G., Limet J. N. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting analysis of smooth-lipopolysaccharide heterogeneity among Brucella biovars related to A and M specificities. J Clin Microbiol. 1990 Oct;28(10):2169–2174. doi: 10.1128/jcm.28.10.2169-2174.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Limet J. N., Bosseray N., Garin-Bastuji B., Dubray G., Plommet M. Humoral immunity in mice mediated by monoclonal antibodies against the A and M antigens of Brucella. J Med Microbiol. 1989 Sep;30(1):37–43. doi: 10.1099/00222615-30-1-37. [DOI] [PubMed] [Google Scholar]
- Limet J., Plommet A. M., Dubray G., Plommet M. Immunity conferred upon mice by anti-LPS monoclonal antibodies in murine brucellosis. Ann Inst Pasteur Immunol. 1987 May-Jun;138(3):417–424. doi: 10.1016/s0769-2625(87)80052-1. [DOI] [PubMed] [Google Scholar]
- Meikle P. J., Perry M. B., Cherwonogrodzky J. W., Bundle D. R. Fine structure of A and M antigens from Brucella biovars. Infect Immun. 1989 Sep;57(9):2820–2828. doi: 10.1128/iai.57.9.2820-2828.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Montaraz J. A., Winter A. J., Hunter D. M., Sowa B. A., Wu A. M., Adams L. G. Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies. Infect Immun. 1986 Mar;51(3):961–963. doi: 10.1128/iai.51.3.961-963.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Phillips M., Deyoe B. L., Canning P. C. Protection of mice against Brucella abortus infection by inoculation with monoclonal antibodies recognizing Brucella O-antigen. Am J Vet Res. 1989 Dec;50(12):2158–2161. [PubMed] [Google Scholar]