Skip to main content
PMC home page
Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 2002 Jan;94(1):31–39.

Increasing participation of minorities in cancer clinical trials: summary of the "Moving Beyond the Barriers" Conference in North Carolina.

Nancy Stark 1, Electra Paskett 1, Ronny Bell 1, M Robert Cooper 1, Elizabeth Walker 1, Alma Wilson 1, Cathy Tatum 1
PMCID: PMC2594090  PMID: 11837350

Abstract

A day-long seminar was held at Wake Forest University School of Medicine to address barriers among ethnic minorities in cancer clinical trials and explore ways that individuals who design and conduct clinical trials could increase minority representation. Speakers addressed implications of under-representation of minorities and identified barriers to minority participation. State-wide focus group results were presented and revealed suspicion of medical research among minorities and the need for bridging to minority communities to improve participation in cancer clinical trials. Working groups assembled and identified barriers specific to trial design, providers, and participants. Attendees were encouraged to devise strategies within their institutions to overcome barriers to minority participation.

Full text

PDF
33

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Areán P. A., Gallagher-Thompson D. Issues and recommendations for the recruitment and retention of older ethnic minority adults into clinical research. J Consult Clin Psychol. 1996 Oct;64(5):875–880. doi: 10.1037//0022-006x.64.5.875. [DOI] [PubMed] [Google Scholar]
  2. Atkins C. J., Patterson T. L., Roppe B. E., Kaplan R. M., Sallis J. F., Nadar P. R. Recruitment issues, health habits, and the decision to participate in a health promotion program. Am J Prev Med. 1987 Mar-Apr;3(2):87–94. [PubMed] [Google Scholar]
  3. Baines C. J. Impediments to recruitment in the Canadian National Breast Screening Study: response and resolution. Control Clin Trials. 1984 Jun;5(2):129–140. doi: 10.1016/0197-2456(84)90119-3. [DOI] [PubMed] [Google Scholar]
  4. Foster M. W., Bernsten D., Carter T. H. A model agreement for genetic research in socially identifiable populations. Am J Hum Genet. 1998 Sep;63(3):696–702. doi: 10.1086/302013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gorelick P. B., Richardson D., Hudson E., Perry C., Robinson D., Brown N., Harris Y. Establishing a community network for recruitment of African Americans into a clinical trial. The African-American antiplatelet stroke Prevention Study (AAASPS) experience. J Natl Med Assoc. 1996 Nov;88(11):701–704. [PMC free article] [PubMed] [Google Scholar]
  6. Gotay C. C. Accrual to cancer clinical trials: directions from the research literature. Soc Sci Med. 1991;33(5):569–577. doi: 10.1016/0277-9536(91)90214-w. [DOI] [PubMed] [Google Scholar]
  7. Hertert S., Bailey G., Cottinghan V., Carmody S., Egan D., Johnson P., Probstfield J. Community volunteers as recruitment staff in a clinical trial: the systolic hypertension in the elderly program (SHEP) experience. Control Clin Trials. 1996 Feb;17(1):23–32. doi: 10.1016/0197-2456(95)00074-7. [DOI] [PubMed] [Google Scholar]
  8. Hunter C. P., Frelick R. W., Feldman A. R., Bavier A. R., Dunlap W. H., Ford L., Henson D., Macfarlane D., Smart C. R., Yancik R. Selection factors in clinical trials: results from the Community Clinical Oncology Program Physician's Patient Log. Cancer Treat Rep. 1987 Jun;71(6):559–565. [PubMed] [Google Scholar]
  9. Langley C., Gray S., Selley S., Bowie C., Price C. Clinicians' attitudes to recruitment to randomised trials in cancer care: a qualitative study. J Health Serv Res Policy. 2000 Jul;5(3):164–169. doi: 10.1177/135581960000500307. [DOI] [PubMed] [Google Scholar]
  10. Lovato L. C., Hill K., Hertert S., Hunninghake D. B., Probstfield J. L. Recruitment for controlled clinical trials: literature summary and annotated bibliography. Control Clin Trials. 1997 Aug;18(4):328–352. doi: 10.1016/s0197-2456(96)00236-x. [DOI] [PubMed] [Google Scholar]
  11. Macaulay A. C., Cross E. J., Delormier T., Potvin L., Paradis G., McComber A. Developing a Code of Research Ethics for research with a Native community in Canada: a report from the Kahnawake Schools Diabetes Prevention Project. Int J Circumpolar Health. 1998;57 (Suppl 1):38–40. [PubMed] [Google Scholar]
  12. Macaulay A. C., Delormier T., McComber A. M., Cross E. J., Potvin L. P., Paradis G., Kirby R. L., Saad-Haddad C., Desrosiers S. Participatory research with native community of Kahnawake creates innovative Code of Research Ethics. Can J Public Health. 1998 Mar-Apr;89(2):105–108. doi: 10.1007/BF03404399. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. McCusker J., Wax A., Bennett J. M. Cancer patient accessions into clinical trials: a pilot investigation into some patient and physician determinants of entry. Am J Clin Oncol. 1982 Apr;5(2):227–236. doi: 10.1097/00000421-198204000-00072. [DOI] [PubMed] [Google Scholar]
  14. Millon-Underwood S., Sanders E., Davis M. Determinants of participation in state-of-the-art cancer prevention, early detection/screening, and treatment trials among African-Americans. Cancer Nurs. 1993 Feb;16(1):25–33. [PubMed] [Google Scholar]
  15. Mouton C. P., Harris S., Rovi S., Solorzano P., Johnson M. S. Barriers to black women's participation in cancer clinical trials. J Natl Med Assoc. 1997 Nov;89(11):721–727. [PMC free article] [PubMed] [Google Scholar]
  16. Norton I. M., Manson S. M. Research in American Indian and Alaska Native communities: navigating the cultural universe of values and process. J Consult Clin Psychol. 1996 Oct;64(5):856–860. doi: 10.1037//0022-006x.64.5.856. [DOI] [PubMed] [Google Scholar]
  17. Roberson N. L. Clinical trial participation. Viewpoints from racial/ethnic groups. Cancer. 1994 Nov 1;74(9 Suppl):2687–2691. doi: 10.1002/1097-0142(19941101)74:9+<2687::aid-cncr2820741817>3.0.co;2-b. [DOI] [PubMed] [Google Scholar]
  18. Ross S., Grant A., Counsell C., Gillespie W., Russell I., Prescott R. Barriers to participation in randomised controlled trials: a systematic review. J Clin Epidemiol. 1999 Dec;52(12):1143–1156. doi: 10.1016/s0895-4356(99)00141-9. [DOI] [PubMed] [Google Scholar]
  19. Schell L. M., Tarbell A. M. A partnership study of PCBs and the health of Mohawk youth: lessons from our past and guidelines for our future. Environ Health Perspect. 1998 Jun;106 (Suppl 3):833–840. doi: 10.1289/ehp.98106833. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Swanson G. M., Ward A. J. Recruiting minorities into clinical trials: toward a participant-friendly system. J Natl Cancer Inst. 1995 Dec 6;87(23):1747–1759. doi: 10.1093/jnci/87.23.1747. [DOI] [PubMed] [Google Scholar]
  21. Tangrea J. A. Patient participation and compliance in cancer chemoprevention trials: issues and concerns. Proc Soc Exp Biol Med. 1997 Nov;216(2):260–265. doi: 10.3181/00379727-216-44176. [DOI] [PubMed] [Google Scholar]
  22. Taylor K. M., Margolese R. G., Soskolne C. L. Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer. N Engl J Med. 1984 May 24;310(21):1363–1367. doi: 10.1056/NEJM198405243102106. [DOI] [PubMed] [Google Scholar]

Articles from Journal of the National Medical Association are provided here courtesy of National Medical Association

RESOURCES