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. 1985 Sep;49(3):533–537. doi: 10.1128/iai.49.3.533-537.1985

Granulocyte-macrophage colony-stimulating factor in the sera of Schistosoma japonicum-infected mice.

M Owhashi, Y Nawa
PMCID: PMC261195  PMID: 3875558

Abstract

Infection of mice with Schistosoma japonicum engendered high levels of granulocyte-macrophage colony-stimulating factor (GM-CSF) in serum. The rise in GM-CSF levels in serum was closely associated with the acute phase of the infection and seemed to be dependent on the dose of infection. GM-CSF activity was detected as a sharp single peak in DE-52 anion-exchange chromatography and Sephacryl S-200 and Sephadex G-200 gel chromatography and was almost entirely adsorbed to concanavalin A-Sepharose 4B affinity chromatography. The possible immunological and immunopathological importance of GM-CSF in S. japonicum infection is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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