Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1984 Dec;46(3):870–872. doi: 10.1128/iai.46.3.870-872.1984

D-Alanyl-substituted glycerol lipoteichoic acid in culture fluids of Streptococcus mutans strains GS-5 and BHT.

M Levine, B F Movafagh
PMCID: PMC261631  PMID: 6500717

Abstract

The content and D-alanyl ester complement of lipoteichoic acid from stationary-phase culture filtrates of Streptococcus mutans (strains BHT and GS-5; serotypes b and c) were determined chemically and serologically. A third less lipoteichoic acid was obtained from strain GS-5 than from strain BHT. This lipoteichoic acid had an increased mobility on immunoelectrophoresis after exposure overnight at pH 8 and a 10-fold greater content of alanine per mole of glycerol.

Full text

PDF
871

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Archibald A. R., Baddiley J. The teichoic acids. Adv Carbohydr Chem Biochem. 1966;21:323–375. doi: 10.1016/s0096-5332(08)60320-3. [DOI] [PubMed] [Google Scholar]
  2. Brautigan V. M., Childs W. C., 3rd, Neuhaus F. C. Biosynthesis of D-alanyl-lipoteichoic acid in Lactobacillus casei: D-alanyl-lipophilic compounds as intermediates. J Bacteriol. 1981 Apr;146(1):239–250. doi: 10.1128/jb.146.1.239-250.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Cabacungan E., Pieringer R. A. Mode of elongation of the glycerol phosphate polymer of membrane lipoteichoic acid of Streptococcus faecium ATCC 9790. J Bacteriol. 1981 Jul;147(1):75–79. doi: 10.1128/jb.147.1.75-79.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Childs W. C., 3rd, Neuhaus F. C. Biosynthesis of D-alanyl-lipoteichoic acid: characterization of ester-linked D-alanine in the in vitro-synthesized product. J Bacteriol. 1980 Jul;143(1):293–301. doi: 10.1128/jb.143.1.293-301.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Doyle R. J., Chatterjee A. N., Streips U. N., Young F. E. Soluble macromolecular complexes involving bacterial teichoic acids. J Bacteriol. 1975 Oct;124(1):341–347. doi: 10.1128/jb.124.1.341-347.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Fischer W. D-alanine ester-containing glycerophosphoglycolipids in the membrane of gram-positive bacteria. Biochim Biophys Acta. 1982 May 13;711(2):372–375. doi: 10.1016/0005-2760(82)90048-0. [DOI] [PubMed] [Google Scholar]
  7. Hardy L., Jacques N. A., Forester H., Campbell L. K., Knox K. W., Wicken A. J. Effect of fructose and other carbohydrates on the surface properties, lipoteichoic acid production, and extracellular proteins of Streptococcus mutans Ingbritt grown in continuous culture. Infect Immun. 1981 Jan;31(1):78–87. doi: 10.1128/iai.31.1.78-87.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Jacques N. A., Hardy L., Campbell L. K., Knox K. W., Evans J. D., Wicken A. J. Effect of carbohydrate source and growth conditions on the production of lipoteichoic acid by Streptococcus mutans Ingbritt. Infect Immun. 1979 Dec;26(3):1079–1087. doi: 10.1128/iai.26.3.1079-1087.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Jacques N. A., Hardy L., Knox K. W., Wicken A. J. Effect of growth conditions on the formation of extracellular lipoteichoic acid by Streptococcus mutans BHT. Infect Immun. 1979 Jul;25(1):75–84. doi: 10.1128/iai.25.1.75-84.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Levine M., Bush C. M. Human serum precipitins to human dental plaque and oral bacteria. Arch Oral Biol. 1981;26(2):117–122. doi: 10.1016/0003-9969(81)90080-7. [DOI] [PubMed] [Google Scholar]
  11. Levine M. Naturally occurring human serum precipitins specific for D-alanyl esters of glycerol teichoic acid. Mol Immunol. 1982 Jan;19(1):133–142. doi: 10.1016/0161-5890(82)90255-3. [DOI] [PubMed] [Google Scholar]
  12. MCCARTY M. THE ROLE OF D-ALANINE IN THE SEROLOGICAL SPECIFICITY OF GROUP A STREPTOCOCCAL GLYCEROL TEICHOIC ACID. Proc Natl Acad Sci U S A. 1964 Aug;52:259–265. doi: 10.1073/pnas.52.2.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Wicken A. J., Gibbens J. W., Knox K. W. Comparative studies on the isolation of membrane lipoteichoic acid from Lactobacillus fermenti. J Bacteriol. 1973 Jan;113(1):365–372. doi: 10.1128/jb.113.1.365-372.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES