Abstract
A greater percentage of the inner-city black population suffers from chronic obstructive pulmonary disease (COPD) than does the white population in general. Urban black patients are also more likely than urban white patients to receive primary care for their COPD symptoms in area emergency rooms, which can affect the resources available for medical care in these institutions. The present study compared the standard of therapy at Provident Medical Center, metaproterenol, administered by a hand-held nebulizer (HHN), with therapy using terbutaline, administered by a metered-dose inhaler (MDI) with a spacer, in 60 black patients with mild to moderate respiratory distress.
Measurements of peak expiratory flow rates before and after therapy indicated that both methods of treatment provided similar relief. The terbutaline MDI modality, however, required less equipment and therapist time, and patients could continue the same therapy at home. All 60 patients were sent home on terbutaline MDI therapy. Follow-up by questionnaire, two to three weeks later, showed 95 percent of 36 respondents preferred the terbutaline MDI with spacer compared with their previous therapy.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bhat B. R., Friedman S., Adimoolam S., Schneider A. T., Chiaramonte L. T. Study of social, educational, environmental and cultural aspects of childhood asthma in clinic and private patients in the city of New York. Ann Allergy. 1978 Aug;41(2):89–92. [PubMed] [Google Scholar]
- Chester E. H., Doggett W. E., Montenegro H. D., Schwartz H. J., Jones P. K. Bronchodilating effect of terbutaline aerosol. Clin Pharmacol Ther. 1978 Jun;23(6):630–634. doi: 10.1002/cpt1978236630. [DOI] [PubMed] [Google Scholar]
- Formgren H. Clinical comparison of inhaled terbutaline and orciprenaline in asthmatic patients. Scand J Respir Dis. 1970;51(3):203–211. [PubMed] [Google Scholar]
- Freedman B. J. Trial of a terbutaline aerosol in the treatment of asthma and a comparison of its effects with those of a salbutamol aerosol. Br J Dis Chest. 1972 Jul;66(3):222–229. [PubMed] [Google Scholar]
- Grundbacher F. J. Causes of variation in serum IgE levels in normal populations. J Allergy Clin Immunol. 1975 Aug;56(2):104–111. doi: 10.1016/0091-6749(75)90114-1. [DOI] [PubMed] [Google Scholar]
- Grundbacher F. J., Massie F. S. Levels of immunoglobulin G, M, A, and E at various ages in allergic and nonallergic black and white individuals. J Allergy Clin Immunol. 1985 Jun;75(6):651–658. doi: 10.1016/0091-6749(85)90089-2. [DOI] [PubMed] [Google Scholar]
- Karetzky M. S. Asthma in the South Bronx: clinical and epidemiologic characteristics. J Allergy Clin Immunol. 1977 Dec;60(6):383–390. doi: 10.1016/0091-6749(77)90070-7. [DOI] [PubMed] [Google Scholar]
- Mak H., Johnston P., Abbey H., Talamo R. C. Prevalence of asthma and health service utilization of asthmatic children in an inner city. J Allergy Clin Immunol. 1982 Nov;70(5):367–372. doi: 10.1016/0091-6749(82)90026-4. [DOI] [PubMed] [Google Scholar]
- Menkes H. A., Cohen B. H., Levy D. A., Kreiss P., Permutt S., Tielsh J. Genetic factors in chronic obstructive lung disease. Bull Eur Physiopathol Respir. 1980;16 (Suppl):357–366. doi: 10.1016/b978-0-08-027379-2.50037-5. [DOI] [PubMed] [Google Scholar]
- Mullally D. I., Howard W. A., Hubbard T. J., Grauman J. S., Cohen S. G. Increased hospitalizations for asthma among children in the Washington, D.C. area during 1961-1981. Ann Allergy. 1984 Jul;53(1):15–19. [PubMed] [Google Scholar]
- Møller N. E., Hyldgaard-Jensen N. C. Bivirkninger ved aerosolbehandling med freondrivgasser hos asthma- og cystisk fibrose patienter. Ugeskr Laeger. 1979 Oct 15;141(42):2892–2893. [PubMed] [Google Scholar]
- Roth M. J., Wilson A. F., Novey H. S. A comparative study of the aerosolized bronchodilators, isoproterenol, metaproterenol and terbutaline in asthma. Ann Allergy. 1977 Jan;38(1):16–21. [PubMed] [Google Scholar]
- Schenker M. B., Samet J. M., Speizer F. E. Risk factors for childhood respiratory disease. The effect of host factors and home environmental exposures. Am Rev Respir Dis. 1983 Dec;128(6):1038–1043. doi: 10.1164/arrd.1983.128.6.1038. [DOI] [PubMed] [Google Scholar]
- Sherry M. N., Scott R. B. Prevalence of allergic diseases in freshman college students: a survey based on a predominately Negro population. Ann Allergy. 1968 Jul;26(7):335–338. [PubMed] [Google Scholar]