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. 1984 Jan;43(1):66–71. doi: 10.1128/iai.43.1.66-71.1984

Effect of type A Pasteurella multocida fractions on bovine polymorphonuclear leukocyte functions.

H Ryu, M L Kaeberle, J A Roth, R W Griffith
PMCID: PMC263389  PMID: 6690417

Abstract

The effect of various Pasteurella multocida fractions on bovine polymorphonuclear leukocyte (PMN) functions was examined in vitro by using two encapsulated strains, P-2383 and P-1062 (both are Carter capsular type A and of bovine origin). The ability of PMNs to ingest Staphylococcus aureus and iodinate protein was significantly inhibited in the presence of live cells, heat-killed whole cells, or saline-extracted capsules but not in the presence of the decapsulated heat-killed cells. None of the fractions of the two strains inhibited nitroblue tetrazolium reduction by PMNs. The saline extract did not inhibit the binding of iodine to protein by a reaction involving xanthine, xanthine oxidase, and horseradish peroxidase. The PMN inhibitory factor was further characterized as a heat-stable capsular material of greater than 300,000 molecular weight.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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