Abstract
PCR amplification of a species-specific 2-kb KpnI fragment of variable size located 10 kb upstream of the katG gene was used to subdivide 130 clinical isolates of Mycobacterium tuberculosis. Seven subtypes were identified, and their frequencies were distributed normally with respect to the size of the amplified product.
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- Cave M. D., Eisenach K. D., Templeton G., Salfinger M., Mazurek G., Bates J. H., Crawford J. T. Stability of DNA fingerprint pattern produced with IS6110 in strains of Mycobacterium tuberculosis. J Clin Microbiol. 1994 Jan;32(1):262–266. doi: 10.1128/jcm.32.1.262-266.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Edlin B. R., Tokars J. I., Grieco M. H., Crawford J. T., Williams J., Sordillo E. M., Ong K. R., Kilburn J. O., Dooley S. W., Castro K. G. An outbreak of multidrug-resistant tuberculosis among hospitalized patients with the acquired immunodeficiency syndrome. N Engl J Med. 1992 Jun 4;326(23):1514–1521. doi: 10.1056/NEJM199206043262302. [DOI] [PubMed] [Google Scholar]
- Goyal M., Ormerod L. P., Shaw R. J. Epidemiology of an outbreak of drug-resistant tuberculosis in the U.K. using restriction fragment length polymorphism. Clin Sci (Lond) 1994 Jun;86(6):749–751. doi: 10.1042/cs0860749. [DOI] [PubMed] [Google Scholar]
- Otal I., Martín C., Vincent-Lévy-Frebault V., Thierry D., Gicquel B. Restriction fragment length polymorphism analysis using IS6110 as an epidemiological marker in tuberculosis. J Clin Microbiol. 1991 Jun;29(6):1252–1254. doi: 10.1128/jcm.29.6.1252-1254.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Palittapongarnpim P., Chomyc S., Fanning A., Kunimoto D. DNA fragment length polymorphism analysis of Mycobacterium tuberculosis isolates by arbitrarily primed polymerase chain reaction. J Infect Dis. 1993 Apr;167(4):975–978. doi: 10.1093/infdis/167.4.975. [DOI] [PubMed] [Google Scholar]
- Plikaytis B. B., Crawford J. T., Woodley C. L., Butler W. R., Eisenach K. D., Cave M. D., Shinnick T. M. Rapid, amplification-based fingerprinting of Mycobacterium tuberculosis. J Gen Microbiol. 1993 Jul;139(7):1537–1542. doi: 10.1099/00221287-139-7-1537. [DOI] [PubMed] [Google Scholar]
- Ross B. C., Raios K., Jackson K., Dwyer B. Molecular cloning of a highly repeated DNA element from Mycobacterium tuberculosis and its use as an epidemiological tool. J Clin Microbiol. 1992 Apr;30(4):942–946. doi: 10.1128/jcm.30.4.942-946.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zhang Y., Garbe T., Young D. Transformation with katG restores isoniazid-sensitivity in Mycobacterium tuberculosis isolates resistant to a range of drug concentrations. Mol Microbiol. 1993 May;8(3):521–524. doi: 10.1111/j.1365-2958.1993.tb01596.x. [DOI] [PubMed] [Google Scholar]
- Zhang Y., Heym B., Allen B., Young D., Cole S. The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Nature. 1992 Aug 13;358(6387):591–593. doi: 10.1038/358591a0. [DOI] [PubMed] [Google Scholar]