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. 1983 Sep;41(3):1010–1015. doi: 10.1128/iai.41.3.1010-1015.1983

Toxicity but not arthritogenicity of Mycoplasma arthritidis for mice associates with the haplotype expressed at the major histocompatibility complex.

B C Cole, R N Thorpe, L A Hassell, L R Washburn, J R Ward
PMCID: PMC264601  PMID: 6885154

Abstract

The use of inbred and congenic mouse strains established that toxicity and death induced by Mycoplasma arthritidis associates with the haplotype expressed at the murine major histocompatibility complex. Mice bearing H-2k and H-2d are susceptible, whereas those bearing H-2b are much more resistant. Mice susceptible to toxicity exhibited massive peritoneal adhesions and a decreased ability to clear organisms from the peripheral circulation. However, the severity of acute arthritis developing over a 3-month period was not statistically related to the haplotype expressed at the major histocompatibility complex. Lymphocyte activation in vitro by a soluble T-cell mitogen is also dependent on a similar haplotype expression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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