Skip to main content
PMC home page
Infection and Immunity logoLink to Infection and Immunity
. 1983 May;40(2):836–839. doi: 10.1128/iai.40.2.836-839.1983

Surface antigens of metacyclic trypomastigotes of Trypanosoma cruzi.

N Yoshida
PMCID: PMC264932  PMID: 6341250

Abstract

The surface antigen makeup of metacyclic trypomastigote forms of strain G of Trypanosoma cruzi, which produce a subpatent infection in mice, differed from those of the virulent strains Y and CL. A 100,000-molecular-weight protein, barely detectable on the Y or CL cell surface, appeared as the main surface antigen of the G metacyclic trypomastigotes. In addition, the G metacyclic forms differed from those of the virulent strains in their susceptibility to complement-mediated immunolysis.

Full text

PDF
839

Images in this article

837Image
on p.837
837Image
on p.837

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Araujo F. G., Remington J. S. Characterization of stages and strains of Trypanosoma cruzi by analysis of cell membrane components. J Immunol. 1981 Sep;127(3):855–859. [PubMed] [Google Scholar]
  2. BRENER Z., CHIARI E. VARIA C OES MORFOL'OGICAS OBSERVADAS EM DIFERENTES AMOSTRAS DE TRYPANOSOMA CRUZI. Rev Inst Med Trop Sao Paulo. 1963 Sep-Oct;5:220–224. [PubMed] [Google Scholar]
  3. CAMARGO E. P. GROWTH AND DIFFERENTIATION IN TRYPANOSOMA CRUZI. I. ORIGIN OF METACYCLIC TRYPANOSOMES IN LIQUID MEDIA. Rev Inst Med Trop Sao Paulo. 1964 May-Jun;6:93–100. [PubMed] [Google Scholar]
  4. Camargo E. P., Mattei D. M., Barbieri C. L., Morel C. M. Electrophoretic analysis of endonuclease-generated fragments of k-DNA, of esterase isoenzymes, and of surface proteins as aids for species identification of insect trypanosomatids. J Protozool. 1982 May;29(2):251–258. doi: 10.1111/j.1550-7408.1982.tb04022.x. [DOI] [PubMed] [Google Scholar]
  5. Kessler S. W. Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. J Immunol. 1975 Dec;115(6):1617–1624. [PubMed] [Google Scholar]
  6. Kierszenbaum F. Cross-reactivity of lytic antibodies against blood forms of Trypanosoma cruzi. J Parasitol. 1976 Feb;62(1):134–135. [PubMed] [Google Scholar]
  7. Krettli A. U., Brener Z. Resistance against Trypanosoma cruzi associated to anti-living trypomastigote antibodies. J Immunol. 1982 May;128(5):2009–2012. [PubMed] [Google Scholar]
  8. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970 Aug 15;227(5259):680–685. doi: 10.1038/227680a0. [DOI] [PubMed] [Google Scholar]
  9. Markwell M. A., Fox C. F. Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3alpha,6alpha-diphenylglycoluril. Biochemistry. 1978 Oct 31;17(22):4807–4817. doi: 10.1021/bi00615a031. [DOI] [PubMed] [Google Scholar]
  10. Nogueira N., Chaplan S., Tydings J. D., Unkeless J., Cohn Z. Trypanosoma cruzi. Surface antigens of blood and culture forms. J Exp Med. 1981 Mar 1;153(3):629–639. doi: 10.1084/jem.153.3.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Snary D. Trypanosoma cruzi: antigenic invariance of the cell surface glycoprotein. Exp Parasitol. 1980 Feb;49(1):68–77. doi: 10.1016/0014-4894(80)90057-0. [DOI] [PubMed] [Google Scholar]
  12. Yoshida N. A macromolecule-free partially defined medium for Trypanosoma cruzi. J Protozool. 1975 Feb;22(1):128–130. doi: 10.1111/j.1550-7408.1975.tb00957.x. [DOI] [PubMed] [Google Scholar]
  13. Yoshida N., Potocnjak P., Nussenzweig V., Nussenzweig R. S. Biosynthesis of Pb44, the protective antigen of sporozoites of Plasmodium berghei. J Exp Med. 1981 Oct 1;154(4):1225–1236. doi: 10.1084/jem.154.4.1225. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES