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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1988 Jan;26(1):88–91. doi: 10.1128/jcm.26.1.88-91.1988

Infection and diarrhea caused by Cryptosporidium sp. among Guatemalan infants.

J R Cruz 1, F Cano 1, P Càceres 1, F Chew 1, G Pareja 1
PMCID: PMC266196  PMID: 3343318

Abstract

During July 1985 to June 1986, fecal excretion of Cryptosporidium oocysts was determined prospectively in a cohort of 130 infants, aged 0 to 11 months, living in a marginal urban area of Guatemala City, Guatemala. A total of 1,280 stool specimens were examined; 158 of them were collected during episodes of diarrhea, and 1,122 were collected during symptom-free periods, every 2 to 3 weeks, from every child. Of the children, 20 (15.4%) excreted Cryptosporidium oocysts during the observation period. Of the diarrheal episodes, 13 (8.3%) were associated with Cryptosporidium sp. Of the control specimens, seven (0.6%) were positive for oocysts. Most of the infections were documented during the months of February to May, at the end of the dry season. Cryptosporidium infections are very common among Guatemalan infants and are an important cause of diarrhea and weight loss. The introduction of liquid or solid foods in the diets of the children, the presence of domestic animals (dogs, cats, or poultry), and the absence of toilet facilities in the house seem to be important risk factors for infection; also, deficient nutritional status may predispose the infected child to Cryptosporidium-associated illness.

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Selected References

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  1. Bogaerts J., Lepage P., Rouvroy D., Vandepitte J. Cryptosporidium spp., a frequent cause of diarrhea in Central Africa. J Clin Microbiol. 1984 Nov;20(5):874–876. doi: 10.1128/jcm.20.5.874-876.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Current W. L., Reese N. C., Ernst J. V., Bailey W. S., Heyman M. B., Weinstein W. M. Human cryptosporidiosis in immunocompetent and immunodeficient persons. Studies of an outbreak and experimental transmission. N Engl J Med. 1983 May 26;308(21):1252–1257. doi: 10.1056/NEJM198305263082102. [DOI] [PubMed] [Google Scholar]
  3. Fayer R., Ungar B. L. Cryptosporidium spp. and cryptosporidiosis. Microbiol Rev. 1986 Dec;50(4):458–483. doi: 10.1128/mr.50.4.458-483.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Garcia L. S., Bruckner D. A., Brewer T. C., Shimizu R. Y. Techniques for the recovery and identification of Cryptosporidium oocysts from stool specimens. J Clin Microbiol. 1983 Jul;18(1):185–190. doi: 10.1128/jcm.18.1.185-190.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Holley H. P., Jr, Dover C. Cryptosporidium: a common cause of parasitic diarrhea in otherwise healthy individuals. J Infect Dis. 1986 Feb;153(2):365–368. doi: 10.1093/infdis/153.2.365. [DOI] [PubMed] [Google Scholar]
  6. Højlyng N., Mølbak K., Jepsen S. Cryptosporidium spp., a frequent cause of diarrhea in Liberian children. J Clin Microbiol. 1986 Jun;23(6):1109–1113. doi: 10.1128/jcm.23.6.1109-1113.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Koch K. L., Phillips D. J., Aber R. C., Current W. L. Cryptosporidiosis in hospital personnel. Evidence for person-to-person transmission. Ann Intern Med. 1985 May;102(5):593–596. doi: 10.7326/0003-4819-102-5-593. [DOI] [PubMed] [Google Scholar]
  8. Mata L., Bolaños H., Pizarro D., Vives M. Cryptosporidiosis in children from some highland Costa Rican rural and urban areas. Am J Trop Med Hyg. 1984 Jan;33(1):24–29. doi: 10.4269/ajtmh.1984.33.24. [DOI] [PubMed] [Google Scholar]
  9. Mathan M. M., Venkatesan S., George R., Mathew M., Mathan V. I. Cryptosporidium and diarrhoea in southern Indian children. Lancet. 1985 Nov 23;2(8465):1172–1175. doi: 10.1016/s0140-6736(85)92691-1. [DOI] [PubMed] [Google Scholar]
  10. Meisel J. L., Perera D. R., Meligro C., Rubin C. E. Overwhelming watery diarrhea associated with a cryptosporidium in an immunosuppressed patient. Gastroenterology. 1976 Jun;70(6):1156–1160. [PubMed] [Google Scholar]
  11. Morris G. K., Merson M. H., Sack D. A., Wells J. G., Martin W. T., Dewitt W. E., Feeley J. C., Sack R. B., Bessudo D. M. Laboratory investigation of diarrhea in travelers to Mexico: evaluation of methods for detecting enterotoxigenic Echerichia coli. J Clin Microbiol. 1976 May;3(5):486–495. doi: 10.1128/jcm.3.5.486-495.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Perez-Schael I., Boher Y., Mata L., Perez M., Tapia F. J. Cryptosporidiosis in Venezuelan children with acute diarrhea. Am J Trop Med Hyg. 1985 Jul;34(4):721–722. doi: 10.4269/ajtmh.1985.34.721. [DOI] [PubMed] [Google Scholar]
  13. Sack D. A., Sack R. B. Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture. Infect Immun. 1975 Feb;11(2):334–336. doi: 10.1128/iai.11.2.334-336.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Shahid N. S., Rahman A. S., Anderson B. C., Mata L. J., Sanyal S. C. Cryptosporidiosis in Bangladesh. Br Med J (Clin Res Ed) 1985 Jan 12;290(6462):114–115. doi: 10.1136/bmj.290.6462.114. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Weisburger W. R., Hutcheon D. F., Yardley J. H., Roche J. C., Hillis W. D., Charache P. Cryptosporidiosis in an immunosuppressed renal-transplant recipient with IgA deficiency. Am J Clin Pathol. 1979 Sep;72(3):473–478. doi: 10.1093/ajcp/72.3.473. [DOI] [PubMed] [Google Scholar]
  16. Yolken R. H., Kim H. W., Clem T., Wyatt R. G., Kalica A. R., Chanock R. M., Kapikian A. Z. Enzyme-linked immunosorbent assay (ELISA) for detection of human reovirus-like agent of infantile gastroenteritis. Lancet. 1977 Aug 6;2(8032):263–267. doi: 10.1016/s0140-6736(77)90951-5. [DOI] [PubMed] [Google Scholar]
  17. van den Ende G. M. Cryptosporidiosis among black children in hospital in South Africa. J Infect. 1986 Jul;13(1):25–30. doi: 10.1016/s0163-4453(86)92164-x. [DOI] [PubMed] [Google Scholar]

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