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. 1993 Dec;31(12):3184–3189. doi: 10.1128/jcm.31.12.3184-3189.1993

Differentiation of U.S. and European isolates of porcine reproductive and respiratory syndrome virus by monoclonal antibodies.

E A Nelson 1, J Christopher-Hennings 1, T Drew 1, G Wensvoort 1, J E Collins 1, D A Benfield 1
PMCID: PMC266373  PMID: 7508455

Abstract

Monoclonal antibodies (MAbs) to two U.S. isolates of porcine reproductive and respiratory syndrome (PRRS) virus were prepared. Two MAbs specifically recognized a conserved epitope on the putative 15-kDa nucleocapsid protein of U.S. and European isolates of PRRS virus. Four other MAbs recognized epitopes on the 15-kDa protein of U.S. but not European isolates of PRRS virus. Collectively, this indicates that PRRS viruses contain both conserved and divergent epitopes on the 15-kDa viral protein.

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Selected References

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