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. 1988 Apr;26(4):625–629. doi: 10.1128/jcm.26.4.625-629.1988

Restriction endonuclease analysis of DNA from Chlamydia trachomatis biovars.

E M Peterson 1, L M de la Maza 1
PMCID: PMC266391  PMID: 2835386

Abstract

DNA from a total of 60 Chlamydia trachomatis isolates was examined by restriction endonuclease analysis. Strains from all established biovars and serovars were tested. There was great diversity between the mouse biovar and the lymphogranuloma venereum (LGV) and trachoma biovars. The LGV and trachoma biovar isolates generated similar fragment patterns; however, distinct fragments appeared to be unique to both biovars, thus allowing differentiation of these two major groups. In most cases, strains of the same serovar could be differentiated from one another when a battery of restriction enzymes was used. In addition, in some cases, certain restriction fragments appeared to be characteristic of strains from a particular geographical location. The DNA patterns generated by all C. trachomatis isolates differed greatly from the DNA patterns generated from the Chlamydia psittaci isolates tested, including TWAR, a human C. psittaci strain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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