Skip to main content
NCBI home page
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1985 Nov;22(5):838–840. doi: 10.1128/jcm.22.5.838-840.1985

Enteropathogenic Escherichia coli diarrhea in hospitalized children in Bangladesh.

M Moyenuddin, K M Rahman
PMCID: PMC268538  PMID: 3902881

Abstract

The role of enteropathogenic Escherichia coli (EPEC) was evaluated in a group of children with endemic diarrhea admitted to Dhaka Shishu Hospital in Dacca, Bangladesh. EPEC was detected in fecal samples of 23% of 104 cases and 8% of 74 concurrent control children. The most commonly isolated EPEC strains were serogroups O20a, O20c:K61; O20a, O20b:K84; O26:K60; and O18a, O18c:K77. Except for O26:K60, these groups had not been reported from Bangladesh. On testing for enterotoxin production, only two strains (serogroups O26:K60, O18a, and O18c:K77) were enterotoxigenic. None was enteroinvasive as tested in the guinea pig conjunctivitis model. Our study supports the concept that EPEC may be an important cause of endemic diarrhea in Bangladesh.

Full text

PDF
839

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Darfeuille A., Lafeuille B., Joly B., Cluzel R. A new colonization factor antigen (CFA/III) produced by enteropathogenic Escherichia coli O128:B12. Ann Microbiol (Paris) 1983 Jan-Feb;134A(1):53–64. doi: 10.1016/0769-2609(83)90103-5. [DOI] [PubMed] [Google Scholar]
  2. Edelman R., Levine M. M. From the National Institute of Allergy and Infectious Diseases. Summary of a workshop on enteropathogenic Escherichia coli. J Infect Dis. 1983 Jun;147(6):1108–1118. doi: 10.1093/infdis/147.6.1108. [DOI] [PubMed] [Google Scholar]
  3. Etkin S., Gorbach S. L. Studies on enterotoxin from Escherichia coli associated with acute diarrhea in man. J Lab Clin Med. 1971 Jul;78(1):81–87. [PubMed] [Google Scholar]
  4. Ganguly U., Sen D., Dutta P., Pal S. C. Enterotoxigenic Escherichia coli associated diarrhoea in children and adults at a hospital in Calcutta. Indian J Med Res. 1980 Apr;71:498–500. [PubMed] [Google Scholar]
  5. Goldschmidt M. C., DuPont H. L. Enteropathogenic Escherichia coli: lack of correlation of serotype with pathogenicity. J Infect Dis. 1976 Feb;133(2):153–156. doi: 10.1093/infdis/133.2.153. [DOI] [PubMed] [Google Scholar]
  6. Guerrant R. L., Brunton L. L., Schnaitman T. C., Rebhun L. I., Gilman A. G. Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. Infect Immun. 1974 Aug;10(2):320–327. doi: 10.1128/iai.10.2.320-327.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gurwith M. J., Williams T. W. Gastroenteritis in children: a two-year review in Manitoba. I. Etiology. J Infect Dis. 1977 Aug;136(2):239–247. doi: 10.1093/infdis/136.2.239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Kanwar A., Mittal S. K., Ramachandran V. G., Varghese A. A critical study of Escherichia coli as a pathogen in acute gastroenteritis. Indian Pediatr. 1983 Feb;20(2):113–119. [PubMed] [Google Scholar]
  9. Klipstein F. A., Rowe B., Engert R. F., Short H. B., Gross R. J. Enterotoxigenicity of enteropathogenic serotypes of Escherichia coli isolated from infants with epidemic diarrhea. Infect Immun. 1978 Jul;21(1):171–178. doi: 10.1128/iai.21.1.171-178.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Konowalchuk J., Speirs J. I., Stavric S. Vero response to a cytotoxin of Escherichia coli. Infect Immun. 1977 Dec;18(3):775–779. doi: 10.1128/iai.18.3.775-779.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. MACKEL D. C., LANGLEY L. F., VENICE L. A. The use of the guinea-pig conjunctivae as an experimental model for the study of virulence of Shigella organisms. Am J Hyg. 1961 Mar;73:219–223. doi: 10.1093/oxfordjournals.aje.a120179. [DOI] [PubMed] [Google Scholar]
  12. Moffet H. L., Shulenberger H. K., Burkholder E. R. Epidemiology and etiology of severe infantile diarrhea. J Pediatr. 1968 Jan;72(1):1–14. doi: 10.1016/s0022-3476(68)80394-4. [DOI] [PubMed] [Google Scholar]
  13. Mäki M., Vesikari T., Grönroos P. Enterotoxigenic and invasive Escherichia coli as causes of childhood diarrhoea in Finland. Acta Paediatr Scand. 1980 Mar;69(2):219–224. doi: 10.1111/j.1651-2227.1980.tb07064.x. [DOI] [PubMed] [Google Scholar]
  14. NETER E. Enteritis due to enteropathogenic Escherichia coli; present-day status and unsolved problems. J Pediatr. 1959 Aug;55(2):223–239. doi: 10.1016/s0022-3476(59)80091-3. [DOI] [PubMed] [Google Scholar]
  15. PRAKASH O. Escherichia coli serotypes isolated from sporadic cases of diarrhoea and gastroenteritis in infants in Delhi. Indian J Med Res. 1962 Jul;50:607–611. [PubMed] [Google Scholar]
  16. Sack R. B., Hirschhorn N., Brownlee I., Cash R. A., Woodward W. E., Sack D. A. Enterotoxigenic Escherichia-coli-associated diarrheal disease in Apache children. N Engl J Med. 1975 May 15;292(20):1041–1045. doi: 10.1056/NEJM197505152922001. [DOI] [PubMed] [Google Scholar]
  17. Sakazaki R., Tamura K., Nakamura A. Further studies on enteropathogenic Escherichia coli associated with diarrhoeal diseases in children and adults. Jpn J Med Sci Biol. 1974 Feb;27(1):7–18. doi: 10.7883/yoken1952.27.7. [DOI] [PubMed] [Google Scholar]
  18. Sakazaki R., Tamura K., Saito M. Enteropathogenic Escherichia coli associated with diarrhea in children and adults. Jpn J Med Sci Biol. 1967 Oct;20(5):387–399. doi: 10.7883/yoken1952.20.387. [DOI] [PubMed] [Google Scholar]
  19. Sarkar R., Chowdhuri A. N., Dutta J. K., Sehgal H., Mohan M. Enteropathogenic Escherichia coli associated with diarrhoeal diseases in children. Indian J Med Res. 1980 Apr;71:493–497. [PubMed] [Google Scholar]
  20. Sen D., Saha M. R., Niyogi S. K., Nair G. B., De S. P., Datta P., Datta D., Pal S. C., Bose R., Roychowdhury J. Aetiological studies on hospital in-patients with acute diarrhoea in Calcutta. Trans R Soc Trop Med Hyg. 1983;77(2):212–214. doi: 10.1016/0035-9203(83)90073-1. [DOI] [PubMed] [Google Scholar]
  21. Tewari L., Agarwal S. K., Khan A. M., Kumar A., Mehrotra R. M. Prevalence of Escherichia coli serotypes enteropathogenic to man at Lucknow. Indian J Med Res. 1979 Feb;69:225–230. [PubMed] [Google Scholar]
  22. Thorén A. The role of enteropathogenic E. coli in infantile diarrhoea. Aspects on bacteriology, epidemiology and therapy. Scand J Infect Dis Suppl. 1983;37:1–51. doi: 10.3109/inf.1982.14.suppl-37.01. [DOI] [PubMed] [Google Scholar]
  23. Toledo M. R., Alvariza M. do C., Murahovschi J., Ramos S. R., Trabulsi L. R. Enteropathogenic Escherichia coli serotypes and endemic diarrhea in infants. Infect Immun. 1983 Feb;39(2):586–589. doi: 10.1128/iai.39.2.586-589.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Williams P. H., Sedgwick M. I., Evans N., Turner P. J., George R. H., McNeish A. S. Adherence of an enteropathogenic strain of Escherichia coli to human intestinal mucosa is mediated by a colicinogenic conjugative plasmid. Infect Immun. 1978 Nov;22(2):393–402. doi: 10.1128/iai.22.2.393-402.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES