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. 1987 Oct;25(10):2028–2029. doi: 10.1128/jcm.25.10.2028-2029.1987

Evaluation of coagulase-negative staphylococci for ability to produce toxic shock syndrome toxin 1.

B N Kreiswirth 1, P M Schlievert 1, R P Novick 1
PMCID: PMC269397  PMID: 3117846

Abstract

A large and diverse group of coagulase-negative staphylococci were assayed for the ability to produce toxic shock syndrome toxin 1 (TSST-1) by immunological reactivity, and whole-cell DNAs from 33 of these strains were hybridized with a TSST-1-specific gene probe. None of the strains tested, including isolates that have been reported as TSST-1+, produced the exotoxin, and no DNA homology was found with the gene probe.

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Selected References

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  1. Bergdoll M. S., Crass B. A., Reiser R. F., Robbins R. N., Davis J. P. A new staphylococcal enterotoxin, enterotoxin F, associated with toxic-shock-syndrome Staphylococcus aureus isolates. Lancet. 1981 May 9;1(8228):1017–1021. doi: 10.1016/s0140-6736(81)92186-3. [DOI] [PubMed] [Google Scholar]
  2. Blomster-Hautamaa D. A., Kreiswirth B. N., Kornblum J. S., Novick R. P., Schlievert P. M. The nucleotide and partial amino acid sequence of toxic shock syndrome toxin-1. J Biol Chem. 1986 Nov 25;261(33):15783–15786. [PubMed] [Google Scholar]
  3. Crass B. A., Bergdoll M. S. Involvement of coagulase-negative staphylococci in toxic shock syndrome. J Clin Microbiol. 1986 Jan;23(1):43–45. doi: 10.1128/jcm.23.1.43-45.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dickgiesser N., Kreiswirth B. N. Determination of aminoglycoside resistance in Staphylococcus aureus by DNA hybridization. Antimicrob Agents Chemother. 1986 May;29(5):930–932. doi: 10.1128/aac.29.5.930. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kahler R. C., Boyce J. M., Bergdoll M. S., Lockwood W. R., Taylor M. R. Toxic shock syndrome associated with TSST-1 producing coagulase-negative staphylococci. Am J Med Sci. 1986 Nov;292(5):310–312. doi: 10.1097/00000441-198611000-00011. [DOI] [PubMed] [Google Scholar]
  6. Kreiswirth B. N., Löfdahl S., Betley M. J., O'Reilly M., Schlievert P. M., Bergdoll M. S., Novick R. P. The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature. 1983 Oct 20;305(5936):709–712. doi: 10.1038/305709a0. [DOI] [PubMed] [Google Scholar]
  7. Mekalanos J. J. Duplication and amplification of toxin genes in Vibrio cholerae. Cell. 1983 Nov;35(1):253–263. doi: 10.1016/0092-8674(83)90228-3. [DOI] [PubMed] [Google Scholar]
  8. Parsonnet J., Harrison A. E., Spencer S. E., Reading A., Parsonnet K. C., Kass E. H. Nonproduction of toxic shock syndrome toxin 1 by coagulase-negative staphylococci. J Clin Microbiol. 1987 Aug;25(8):1370–1372. doi: 10.1128/jcm.25.8.1370-1372.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Schlievert P. M., Blomster D. A. Production of staphylococcal pyrogenic exotoxin type C: influence of physical and chemical factors. J Infect Dis. 1983 Feb;147(2):236–242. doi: 10.1093/infdis/147.2.236. [DOI] [PubMed] [Google Scholar]
  10. Schlievert P. M., Shands K. N., Dan B. B., Schmid G. P., Nishimura R. D. Identification and characterization of an exotoxin from Staphylococcus aureus associated with toxic-shock syndrome. J Infect Dis. 1981 Apr;143(4):509–516. doi: 10.1093/infdis/143.4.509. [DOI] [PubMed] [Google Scholar]
  11. Schlievert P. M. Staphylococcal enterotoxin B and toxic-shock syndrome toxin-1 are significantly associated with non-menstrual TSS. Lancet. 1986 May 17;1(8490):1149–1150. doi: 10.1016/s0140-6736(86)91859-3. [DOI] [PubMed] [Google Scholar]
  12. Shands K. N., Schmid G. P., Dan B. B., Blum D., Guidotti R. J., Hargrett N. T., Anderson R. L., Hill D. L., Broome C. V., Band J. D. Toxic-shock syndrome in menstruating women: association with tampon use and Staphylococcus aureus and clinical features in 52 cases. N Engl J Med. 1980 Dec 18;303(25):1436–1442. doi: 10.1056/NEJM198012183032502. [DOI] [PubMed] [Google Scholar]
  13. Todd J., Fishaut M., Kapral F., Welch T. Toxic-shock syndrome associated with phage-group-I Staphylococci. Lancet. 1978 Nov 25;2(8100):1116–1118. doi: 10.1016/s0140-6736(78)92274-2. [DOI] [PubMed] [Google Scholar]

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