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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1991 Feb;29(2):407–409. doi: 10.1128/jcm.29.2.407-409.1991

Rapid, on-site diagnosis of chlamydial urethritis in men by detection of antigens in urethral swabs and urine.

J Sellors 1, J Mahony 1, D Jang 1, L Pickard 1, S Castriciano 1, S Landis 1, I Stewart 1, W Seidelman 1, I Cunningham 1, M Chernesky 1
PMCID: PMC269779  PMID: 2007651

Abstract

First-void urine (FVU) sediments of 240 men were tested for Chlamydia trachomatis antigens by two enzyme immunoassays, TestPack Chlamydia (15 min) and Chlamydiazyme (3.5 h), and the results were compared with urethral swab culture results. The sensitivity and specificity on FVU sediment for TestPack Chlamydia were 76.2% (32 of 42 specimens) and 95.5% (189 of 198 specimens) versus 81.0% (34 of 42 specimens) and 96.5% (191 of 198 specimens) for Chlamydiazyme, respectively. Rapid, on-site detection of chlamydial antigen in male FVU would shorten the infectious period by hastening diagnosis and treatment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Caul E. O., Paul I. D., Milne J. D., Crowley T. Non-invasive sampling method for detecting Chlamydia trachomatis. Lancet. 1988 Nov 26;2(8622):1246–1247. doi: 10.1016/s0140-6736(88)90831-8. [DOI] [PubMed] [Google Scholar]
  2. Chernesky M. A., Mahony J. B., Castriciano S., Mores M., Stewart I. O., Landis S. J., Seidelman W., Sargeant E. J., Leman C. Detection of Chlamydia trachomatis antigens by enzyme immunoassay and immunofluorescence in genital specimens from symptomatic and asymptomatic men and women. J Infect Dis. 1986 Jul;154(1):141–148. doi: 10.1093/infdis/154.1.141. [DOI] [PubMed] [Google Scholar]
  3. Coleman P., Varitek V., Mushahwar I. K., Marchlewicz B., Safford J., Hansen J., Kurpiewski G., Grier T. TestPack Chlamydia, a new rapid assay for the direct detection of Chlamydia trachomatis. J Clin Microbiol. 1989 Dec;27(12):2811–2814. doi: 10.1128/jcm.27.12.2811-2814.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Jawad A. J., Manuel G., Matthews R., Wise R., Clay J. C. Evaluation of a genus-specific monoclonal antibody in an amplified enzyme-linked immunoassay in the detection of Chlamydia in urine samples from men. Sex Transm Dis. 1990 Apr-Jun;17(2):87–89. doi: 10.1097/00007435-199004000-00008. [DOI] [PubMed] [Google Scholar]
  5. Paul I. D., Caul E. O. Evaluation of three Chlamydia trachomatis immunoassays with an unbiased, noninvasive clinical sample. J Clin Microbiol. 1990 Feb;28(2):220–222. doi: 10.1128/jcm.28.2.220-222.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Washington A. E., Johnson R. E., Sanders L. L., Jr Chlamydia trachomatis infections in the United States. What are they costing us? JAMA. 1987 Apr 17;257(15):2070–2072. [PubMed] [Google Scholar]

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