Skip to main content
PMC home page
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1991 Mar;29(3):642–644. doi: 10.1128/jcm.29.3.642-644.1991

Seroprevalence of helicobacter pylori infection in couples.

G I Perez-Perez 1, S S Witkin 1, M D Decker 1, M J Blaser 1
PMCID: PMC269836  PMID: 2037687

Abstract

We investigated the prevalence of Helicobacter pylori in 277 couples attending an infertility clinic. In total, 96 (17.3%) of the 554 persons were positive; in only 18 (6.6%) of the couples were both persons seropositive. Age was an important predictor for H. pylori infection. For 177 couples, information regarding birthplace, duration of cohabitation, history of ulcer or gastritis, and use of antacid or bismuth compounds was available. None of these variables correlated with H. pylori infection except place of birth; 69.1% of 55 persons born outside the United States were seropositive compared with 8.7% of persons born within the United States (P less than 0.0001). Being a partner of an H. pylori-infected person increased the risk of being infected; however, by multiple logistic regression analysis this effect was entirely explained by age and national origin. These data suggest that in young sexually active adults, person-to-person transmission of H. pylori does not occur or at most occurs infrequently.

Full text

PDF
644

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berkowicz J., Lee A. Person-to-person transmission of Campylobacter pylori. Lancet. 1987 Sep 19;2(8560):680–681. doi: 10.1016/s0140-6736(87)92458-5. [DOI] [PubMed] [Google Scholar]
  2. Blaser M. J. Epidemiology and pathophysiology of Campylobacter pylori infections. Rev Infect Dis. 1990 Jan-Feb;12 (Suppl 1):S99–106. doi: 10.1093/clinids/12.supplement_1.s99. [DOI] [PubMed] [Google Scholar]
  3. Buck G. E., Gourley W. K., Lee W. K., Subramanyam K., Latimer J. M., DiNuzzo A. R. Relation of Campylobacter pyloridis to gastritis and peptic ulcer. J Infect Dis. 1986 Apr;153(4):664–669. doi: 10.1093/infdis/153.4.664. [DOI] [PubMed] [Google Scholar]
  4. Dooley C. P., Cohen H., Fitzgibbons P. L., Bauer M., Appleman M. D., Perez-Perez G. I., Blaser M. J. Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med. 1989 Dec 7;321(23):1562–1566. doi: 10.1056/NEJM198912073212302. [DOI] [PubMed] [Google Scholar]
  5. Drumm B., Perez-Perez G. I., Blaser M. J., Sherman P. M. Intrafamilial clustering of Helicobacter pylori infection. N Engl J Med. 1990 Feb 8;322(6):359–363. doi: 10.1056/NEJM199002083220603. [DOI] [PubMed] [Google Scholar]
  6. Dwyer B., Kaldor J., Tee W., Marakowski E., Raios K. Antibody response to Campylobacter pylori in diverse ethnic groups. Scand J Infect Dis. 1988;20(3):349–350. doi: 10.3109/00365548809032465. [DOI] [PubMed] [Google Scholar]
  7. Kosunen T. U., Hök J., Rautelin H. I., Myllylä G. Age-dependent increase of Campylobacter pylori antibodies in blood donors. Scand J Gastroenterol. 1989 Jan;24(1):110–114. doi: 10.3109/00365528909092247. [DOI] [PubMed] [Google Scholar]
  8. Krajden S., Fuksa M., Anderson J., Kempston J., Boccia A., Petrea C., Babida C., Karmali M., Penner J. L. Examination of human stomach biopsies, saliva, and dental plaque for Campylobacter pylori. J Clin Microbiol. 1989 Jun;27(6):1397–1398. doi: 10.1128/jcm.27.6.1397-1398.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Majewski S. I., Goodwin C. S. Restriction endonuclease analysis of the genome of Campylobacter pylori with a rapid extraction method: evidence for considerable genomic variation. J Infect Dis. 1988 Mar;157(3):465–471. doi: 10.1093/infdis/157.3.465. [DOI] [PubMed] [Google Scholar]
  10. Marshall B. J., Warren J. R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984 Jun 16;1(8390):1311–1315. doi: 10.1016/s0140-6736(84)91816-6. [DOI] [PubMed] [Google Scholar]
  11. Mégraud F., Brassens-Rabbé M. P., Denis F., Belbouri A., Hoa D. Q. Seroepidemiology of Campylobacter pylori infection in various populations. J Clin Microbiol. 1989 Aug;27(8):1870–1873. doi: 10.1128/jcm.27.8.1870-1873.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Perez-Perez G. I., Dworkin B. M., Chodos J. E., Blaser M. J. Campylobacter pylori antibodies in humans. Ann Intern Med. 1988 Jul 1;109(1):11–17. doi: 10.7326/0003-4819-109-1-11. [DOI] [PubMed] [Google Scholar]
  13. Perez-Perez G. I., Taylor D. N., Bodhidatta L., Wongsrichanalai J., Baze W. B., Dunn B. E., Echeverria P. D., Blaser M. J. Seroprevalence of Helicobacter pylori infections in Thailand. J Infect Dis. 1990 Jun;161(6):1237–1241. doi: 10.1093/infdis/161.6.1237. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES