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. 1983 Sep;18(3):480–485. doi: 10.1128/jcm.18.3.480-485.1983

Monoclonal antibodies against group- and type-specific lipopolysaccharide antigens of Vibrio cholerae O:1.

B Gustafsson, T Holme
PMCID: PMC270838  PMID: 6630437

Abstract

Hybrid cell lines producing monoclonal antibodies against the O-antigenic determinants of Vibrio cholerae O:1 have been established. The specificity of the antibodies was ascertained by enzyme-linked immunosorbent assay inhibition experiments by using lipopolysaccharides from V. cholerae O:1 strains and type strains of groups O:2 and O:21. The anti-A antibody was of the immunoglobulin M (IgM) class, whereas the anti-B and -C antibodies were IgG3. The antibodies had a good agglutinating capacity when tested against V. cholerae O:1 strains in the slide agglutination test.

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Selected References

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