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. 1984 Sep;20(3):536–538. doi: 10.1128/jcm.20.3.536-538.1984

Methicillin-resistant Staphylococcus aureus strains in New York City hospitals: inter-hospital spread of resistant strains of type 88.

S Schaefler, D Jones, W Perry, T Baradet, E Mayr, C Rampersad
PMCID: PMC271367  PMID: 6436308

Abstract

A survey of methicillin-resistant strains of Staphylococcus aureus received for phage typing indicated a marked increase of resistant strains received in 1982 and 1983. Of 62 hospitals in New York City which sent strains for phage typing, 35 had methicillin-resistant isolates. A significant development was the presence of strains of the same phage type at several hospitals, indicating a possible inter-hospital spread of these strains. Among strains present at several hospitals, the largest group was of experimental phage type 88. Strains of type 88 were received from 23 hospitals, representing 56% of all methicillin-resistant strains received from New York City hospitals. Strains of type 88 were resistant to all antistaphylococcal antibiotics, with the exception of vancomycin, and represented a major source of nosocomial infections at 13 hospitals. As experimental phage 88 is not routinely used for typing in U.S. laboratories, the nationwide distribution of strains of type 88 is difficult to assess.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aeilts G. D., Sapico F. L., Canawati H. N., Malik G. M., Montgomerie J. Z. Methicillin-resistant-Staphylococcus aureus colonization and infection in a rehabilitation facility. J Clin Microbiol. 1982 Aug;16(2):218–223. doi: 10.1128/jcm.16.2.218-223.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Archer G. L., Mayhall C. G. Comparison of epidemiological markers used in the investigation of an outbreak of methicillin-resistant Staphylococcus aureus infections. J Clin Microbiol. 1983 Aug;18(2):395–399. doi: 10.1128/jcm.18.2.395-399.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bauer A. W., Kirby W. M., Sherris J. C., Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966 Apr;45(4):493–496. [PubMed] [Google Scholar]
  4. Boyce J. M., White R. L., Causey W. A., Lockwood W. R. Burn units as a source of methicillin-resistant Staphylococcus aureus infections. JAMA. 1983 May 27;249(20):2803–2807. [PubMed] [Google Scholar]
  5. Cafferkey M. T., Hone R., Falkiner F. R., Keane C. T., Pomeroy H. Gentamicin and methicillin resistant Staphylococcus aureus in Dublin hospitals: clinical and laboratory studies. J Med Microbiol. 1983 May;16(2):117–127. doi: 10.1099/00222615-16-2-117. [DOI] [PubMed] [Google Scholar]
  6. Crossley K., Landesman B., Zaske D. An outbreak of infections caused by strains of Staphylococcus aureus resistant to methicillin and aminoglycosides. II. Epidemiologic studies. J Infect Dis. 1979 Mar;139(3):280–287. doi: 10.1093/infdis/139.3.280. [DOI] [PubMed] [Google Scholar]
  7. Goullet P., Hieng H. S. Progression de la résistance à la gentamicine et à la tobramycine des souches de Staphylococcus aureus isolées d'infections hospitalières. Nouv Presse Med. 1981 Sep 12;10(32):2645-6, 2651-2. [PubMed] [Google Scholar]
  8. Graham D. R., Correa-Villasenor A., Anderson R. L., Vollman J. H., Baine W. B. Epidemic neonatal gentamicin-methicillin--resistant Staphylococcus aureus infection associated with nonspecific topical use of gentamicin. J Pediatr. 1980 Dec;97(6):972–978. doi: 10.1016/s0022-3476(80)80439-2. [DOI] [PubMed] [Google Scholar]
  9. Haley R. W., Hightower A. W., Khabbaz R. F., Thornsberry C., Martone W. J., Allen J. R., Hughes J. M. The emergence of methicillin-resistant Staphylococcus aureus infections in United States hospitals. Possible role of the house staff-patient transfer circuit. Ann Intern Med. 1982 Sep;97(3):297–308. doi: 10.7326/0003-4819-97-3-297. [DOI] [PubMed] [Google Scholar]
  10. Linnemann C. C., Jr, Mason M., Moore P., Korfhagen T. R., Staneck J. L. Methicillin-resistant Staphylococcus aureus: experience in a general hospital over four years. Am J Epidemiol. 1982 Jun;115(6):941–950. doi: 10.1093/oxfordjournals.aje.a113381. [DOI] [PubMed] [Google Scholar]
  11. Pavillard R., Harvey K., Douglas D., Hewstone A., Andrew J., Collopy B., Asche V., Carson P., Davidson A., Gilbert G. Epidemic of hospital-acquired infection due to methicillin-resistant Staphylococcus aureus in major Victorian hospitals. Med J Aust. 1982 May 29;1(11):451–454. [PubMed] [Google Scholar]
  12. Rosendal K., Bülow P., Bentzon M. W., Eriksen K. R. Staphylococcus aureus strains isolated in Danish hospitals from January 1st, 1966, to December 31st, 1974. Acta Pathol Microbiol Scand B. 1976 Dec;84B(6):359–368. doi: 10.1111/j.1699-0463.1976.tb01953.x. [DOI] [PubMed] [Google Scholar]
  13. Saravolatz L. D., Pohlod D. J., Arking L. M. Community-acquired methicillin-resistant Staphylococcus aureus infections: a new source for nosocomial outbreaks. Ann Intern Med. 1982 Sep;97(3):325–329. doi: 10.7326/0003-4819-97-3-325. [DOI] [PubMed] [Google Scholar]
  14. Schaefler S. Bacteriophage-mediated acquisition of antibiotic resistance by Staphylococcus aureus type 88. Antimicrob Agents Chemother. 1982 Mar;21(3):460–467. doi: 10.1128/aac.21.3.460. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Schaefler S., Jones D., Perry W., Ruvinskaya L., Baradet T., Mayr E., Wilson M. E. Emergence of gentamicin- and methicillin-resistant Staphylococcus aureus strains in New York City hospitals. J Clin Microbiol. 1981 Apr;13(4):754–759. doi: 10.1128/jcm.13.4.754-759.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Schaefler S., Perry W., Jones D. Methicillin-resistant strains of Staphylococcus aureus phage type 92. Antimicrob Agents Chemother. 1979 Jan;15(1):74–80. doi: 10.1128/aac.15.1.74. [DOI] [PMC free article] [PubMed] [Google Scholar]

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