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. 1982 Oct;16(4):659–662. doi: 10.1128/jcm.16.4.659-662.1982

Isolation of Clostridium difficile from hospitalized patients without antibiotic-associated diarrhea or colitis.

N M Varki, T I Aquino
PMCID: PMC272441  PMID: 7153315

Abstract

Stool samples from 100 hospitalized patients and 21 healthy adults, obtained between March and June 1980, were cultured on a special selective medium containing cefoxitin and cycloserine to detect Clostridium difficile. This organism was isolated from 13 of the hospitalized patients and from 1 healthy subject. None of the patients with positive cultures had received antimicrobial therapy in the 3 preceding months. The observed rate of C. difficile isolation from adults not suffering from antibiotic-associated diarrhea or colitis is higher than previously reported. C. difficile culture is not recommended as a substitute for toxin assay in the evaluation of patients with intestinal disorders after antimicrobial chemotherapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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