Abstract
Sink drains from the Veterans Administration Medical Center, University of Oklahoma Health Sciences Center, and the Oklahoma City community were selectively cultured for gentamicin- and amikacin-resistant bacteria. Aminoglycoside-resistant organisms were found in 86% (Veterans Administration Medical Center, 88%; University of Oklahoma Health Sciences Center, 88%; and Oklahoma City community, 77%) of all 233 sink drains sampled. Of 207 sink drains harboring aminoglycoside-resistent organisms, 99% of the organisms were gentamicin resistant and 82% were amikacin resistant. These data suggest that aminoglycoside-resistent organisms are commonly present in the environment.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Craven P. C., Jorgensen J. H., Kaspar R. L., Drutz D. J. Amikacin therapy of patients with multiply antibiotic-resistant Serratia marcescens infections: development of increasing resistance during therapy. Am J Med. 1977 Jun;62(6):902–910. doi: 10.1016/0002-9343(77)90659-3. [DOI] [PubMed] [Google Scholar]
- Drollette D., Litsky B. Y., Litsky W. Pseudomonas profile of an ICU. Hospitals. 1971 Aug 16;45(16):91–96. [PubMed] [Google Scholar]
- Flournoy D. J., Muchmore H. G., Francis E. B. Nosocomial infection linked to handwashing. Hospitals. 1979 Aug 1;53(15):105–107. [PubMed] [Google Scholar]
- Gardner P., Smith D. H., Beer H., Moellering R. C., Jr Recovery of resistance (R) factors from a drug-free community. Lancet. 1969 Oct 11;2(7624):774–776. doi: 10.1016/s0140-6736(69)90482-6. [DOI] [PubMed] [Google Scholar]
- Guerrant R. L., Strausbaugh L. J., Wenzel R. P., Hamory B. H., Sande M. A. Nosocomial bloodstream infections caused by gentamicin-resistant gram-negative bacilli. Am J Med. 1977 Jun;62(6):894–901. doi: 10.1016/0002-9343(77)90658-1. [DOI] [PubMed] [Google Scholar]
- Hummel R. P., Miskell P. W., Altemeier W. A. Antibiotic resistance transfer from nonpathogenic to pathogenic bacteria. Surgery. 1977 Sep;82(3):382–385. [PubMed] [Google Scholar]
- Knittle M. A., Eitzman D. V., Baer H. Role of hand contamination of personnel in the epidemiology of gram-negative nosocomial infections. J Pediatr. 1975 Mar;86(3):433–437. doi: 10.1016/s0022-3476(75)80980-2. [DOI] [PubMed] [Google Scholar]
- McGinnis M. R., Padhye A. A., Ajello L. Storage of stock cultures of filamentous fungi, yeasts, and some aerobic actinomycetes in sterile distilled water. Appl Microbiol. 1974 Aug;28(2):218–222. doi: 10.1128/am.28.2.218-222.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moellering R. C., Jr, Wennersten C., Kunz L. J., Poitras J. W. Resistance to gentamicin, tobramycin and amikacin among clinical isolates of bacteria. Am J Med. 1977 Jun;62(6):873–881. doi: 10.1016/0002-9343(77)90655-6. [DOI] [PubMed] [Google Scholar]
- Moffet H. L., Williams T. Bacteria recovered from distilled water and inhalation therapy equipment. Am J Dis Child. 1967 Jul;114(1):7–12. doi: 10.1001/archpedi.1967.02090220013002. [DOI] [PubMed] [Google Scholar]
- Oberhofer T. R., Rowen J. W., Cunningham G. F. Characterization and identification of gram-negative, nonfermentative bacteria. J Clin Microbiol. 1977 Feb;5(2):208–220. doi: 10.1128/jcm.5.2.208-220.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Poon C. P. Studies on the instantaneous death of airborne Escherichia coli. Am J Epidemiol. 1966 Jul;84(1):1–9. doi: 10.1093/oxfordjournals.aje.a120613. [DOI] [PubMed] [Google Scholar]
- Rennie R. P., Duncan I. B. Emergence of gentamicin-resistant Klebsiella in a general hospital. Antimicrob Agents Chemother. 1977 Feb;11(2):179–184. doi: 10.1128/aac.11.2.179. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Steere A. C., Mallison G. F. Handwashing practices for the prevention of nosocomial infections. Ann Intern Med. 1975 Nov;83(5):683–690. doi: 10.7326/0003-4819-83-5-683. [DOI] [PubMed] [Google Scholar]