Skip to main content
PMC home page
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1980 Nov;12(5):672–675. doi: 10.1128/jcm.12.5.672-675.1980

Regional variations in density of cutaneous propionibacteria: correlation of Propionibacterium acnes populations with sebaceous secretion.

K J McGinley, G F Webster, M R Ruggieri, J J Leyden
PMCID: PMC273669  PMID: 7276142

Abstract

Cutaneous Propionibacterium acnes populations were quantitatively measured in 33 young adults and compared with the rate and composition of sebum secretion in nine skin regions. Bacteriological and lipid analyses were performed on the forehead, cheek, anterior chest, abdomen, lower back, volar forearm, upper inner arm, thigh, and calf. P. acnes populations in these sites correlated significantly with the total amount of lipid produced (r = 0.77) as well as with di- and triglycerides (r = 0.68), squalene and wax esters (r = 0.72), cholesterol and cholesterol esters (r = 0.67), and free fatty acids (r = 0.67).

Full text

PDF
675

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aly R., Maibach H. I. Aerobic microbial flora of intertrigenous skin. Appl Environ Microbiol. 1977 Jan;33(1):97–100. doi: 10.1128/aem.33.1.97-100.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Downing D. T. Photodensitometry in the thin-layer chromatographic analysis of neutral lipids. J Chromatogr. 1968 Nov 5;38(1):91–99. doi: 10.1016/0021-9673(68)85011-3. [DOI] [PubMed] [Google Scholar]
  3. Greene R. S., Downing D. T., Pochi P. E., Strauss J. S. Anatomical variation in the amount and composition of human skin surface lipid. J Invest Dermatol. 1970 Mar;54(3):240–247. doi: 10.1111/1523-1747.ep12280318. [DOI] [PubMed] [Google Scholar]
  4. Kligman A. M., Leyden J. J., McGinley K. J. Bacteriology. J Invest Dermatol. 1976 Jul;67(1):160–168. doi: 10.1111/1523-1747.ep12513007. [DOI] [PubMed] [Google Scholar]
  5. Leyden J. J., McGinley K. J., Mills O. H., Kligman A. M. Age-related changes in the resident bacterial flora of the human face. J Invest Dermatol. 1975 Oct;65(4):379–381. doi: 10.1111/1523-1747.ep12607630. [DOI] [PubMed] [Google Scholar]
  6. Leyden J. J., McGinley K. J., Mills O. H., Kligman A. M. Propionibacterium levels in patients with and without acne vulgaris. J Invest Dermatol. 1975 Oct;65(4):382–384. doi: 10.1111/1523-1747.ep12607634. [DOI] [PubMed] [Google Scholar]
  7. Marples R. R., Downing D. T., Kligman A. M. Control of free fatty acids in human surface lipids by Corynebacterium acnes. J Invest Dermatol. 1971 Feb;56(2):127–131. doi: 10.1111/1523-1747.ep12260695. [DOI] [PubMed] [Google Scholar]
  8. Marples R. R., McGinley K. J. Corynebacterium acnes and other anaerobic diphtheroids from human skin. J Med Microbiol. 1974 Aug;7(3):349–357. doi: 10.1099/00222615-7-3-349. [DOI] [PubMed] [Google Scholar]
  9. McGinley K. J., Webster G. F., Leyden J. J. Regional variations of cutaneous propionibacteria. Appl Environ Microbiol. 1978 Jan;35(1):62–66. doi: 10.1128/aem.35.1.62-66.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Puhvel S. M., Reisner R. M. Effect of fatty acids on the growth of Corynebacterium acnes in vitro. J Invest Dermatol. 1970 Jan;54(1):48–52. doi: 10.1111/1523-1747.ep12551667. [DOI] [PubMed] [Google Scholar]
  11. Rebillo T., Hawk J. L. Skin surface glycerol levels in acne vulgaris. J Invest Dermatol. 1978 Jun;70(6):352–354. doi: 10.1111/1523-1747.ep12543549. [DOI] [PubMed] [Google Scholar]
  12. Williamson P., Kligman A. M. A new method for the quantitative investigation of cutaneous bacteria. J Invest Dermatol. 1965 Dec;45(6):498–503. doi: 10.1038/jid.1965.164. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES