Skip to main content
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1978 Jun;7(6):589–594. doi: 10.1128/jcm.7.6.589-594.1978

Disseminated infection by Fusarium moniliforme during treatment for malignant lymphoma.

N A Young, K J Kwon-Chung, T T Kubota, A E Jennings, R I Fisher
PMCID: PMC275078  PMID: 670381

Abstract

Disseminated infection caused by Fusarium moniliforme is described in a 32-year-old granulocytopenic man with malignant lymphoma being treated with cytotoxic drugs and corticosteroids. Infected skin denuded by antecedent severe varicella-zoster infection was the probable source of fungemia. F. moniliforme grows rapidly on common mycological media as a lavender- to violet-colored mold at 25 to 37 degrees C. Its aerial hyphae produce fusoid macroconidia and characteristic fusiform microconidia in chains. The morphology of hyphae in tissue closely resembles species of Aspergillus and is not diagnostically specific. Morphological characteristics which distinguish cultures of F. moniliforme from other medically important species of Fusarium are discussed.

Full text

PDF
592

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDERSON B., ROBERTS S. S., Jr, GONZALEZ C., CHICK E. W. Mycotic ulcerative keratitis. AMA Arch Ophthalmol. 1959 Aug;62(2):169–197. doi: 10.1001/archopht.1959.04220020003001. [DOI] [PubMed] [Google Scholar]
  2. Abramowsky C. R., Quinn D., Bradford W. D., Conant N. F. Systemic infection by fusarium in a burned child. The emergence of a saprophytic strain. J Pediatr. 1974 Apr;84(4):561–564. doi: 10.1016/s0022-3476(74)80681-5. [DOI] [PubMed] [Google Scholar]
  3. Benjamin R. P., Callaway L., Conant N. F. Facial granuloma associated with fusarium infection. Arch Dermatol. 1970 May;101(5):598–600. [PubMed] [Google Scholar]
  4. Bourguignon R. L., Walsh A. F., Flynn J. C., Baro C., Spinos E. Fusarium species osteomyelitis. Case report. J Bone Joint Surg Am. 1976 Jul;58(5):722–723. [PubMed] [Google Scholar]
  5. Cho C. T., Vats T. S., Lowman J. T., Brandsberg J. W., Tosh F. E. Fusarium solani infection during treatment for acute leukemia. J Pediatr. 1973 Dec;83(6):1028–1031. doi: 10.1016/s0022-3476(73)80543-8. [DOI] [PubMed] [Google Scholar]
  6. Collins M. S., Rinaldi M. G. Cutaneous infection in man caused by Fusarium moniliforme. Sabouraudia. 1977 Jul;15(2):151–160. [PubMed] [Google Scholar]
  7. English M. P., Smith R. J., Harman R. R. The fungal flora of ulcerated legs. Br J Dermatol. 1971 Jun;84(6):567–581. doi: 10.1111/j.1365-2133.1971.tb02546.x. [DOI] [PubMed] [Google Scholar]
  8. Forster R. K., Rebell G. The diagnosis and management of keratomycoses. I. Cause and diagnosis. Arch Ophthalmol. 1975 Oct;93(10):975–978. doi: 10.1001/archopht.1975.01010020769005. [DOI] [PubMed] [Google Scholar]
  9. Gugnani H. C., Talwar R. S., Njoku-Obi A. N., Kodilinye H. C. Mycotic keratitis in Nigeria. A study of 21 cases. Br J Ophthalmol. 1976 Sep;60(9):607–613. doi: 10.1136/bjo.60.9.607. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Gutmann L., Chou S. M., Pore R. S. Fusariosis, myasthenic syndrome, and aplastic anemia. Neurology. 1975 Oct;25(10):922–926. doi: 10.1212/wnl.25.10.922. [DOI] [PubMed] [Google Scholar]
  11. Jones B. R. Principles in the management of oculomycosis. XXXI Edward Jackson memorial lecture. Am J Ophthalmol. 1975 May;79(5):719–751. doi: 10.1016/0002-9394(75)90730-8. [DOI] [PubMed] [Google Scholar]
  12. Jones D. B., Forster F. K., Rebell G. Fusarium solani keratitis treated with natamycin (pimaricin): eighteen consecutive cases. Arch Ophthalmol. 1972 Aug;88(2):147–154. doi: 10.1001/archopht.1972.01000030149004. [DOI] [PubMed] [Google Scholar]
  13. Jones D. B., Sexton R., Rebell G. Mycotic keratitis in South Florida: a review of thirty-nine cases. Trans Ophthalmol Soc U K. 1970;89:781–797. [PubMed] [Google Scholar]
  14. Kidd G. H., Wolf F. T. Dimorphism in a pathogenic Fusarium. Mycologia. 1973 Nov-Dec;65(6):1371–1375. [PubMed] [Google Scholar]
  15. Polack F. M., Kaufman H. E., Newmark E. Keratomycosis. Medical and surgical treatment. Arch Ophthalmol. 1971 Apr;85(4):410–416. doi: 10.1001/archopht.1971.00990050412003. [DOI] [PubMed] [Google Scholar]
  16. Singh G., Malik S. R. Therapeutic keratoplasty in fungal corneal ulcers. Br J Ophthalmol. 1972 Jan;56(1):41–45. doi: 10.1136/bjo.56.1.41. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Zapater R. C., Arrechea A. Mycotic keratitis by Fusarium. A review and report of two cases. Ophthalmologica. 1975;170(1):1–12. doi: 10.1159/000307154. [DOI] [PubMed] [Google Scholar]
  18. Zapater R. C., De Arrechea A., Guevara V. H. Quertomicosis por Fusarium dimerum. Sabouraudia. 1972 Nov;10(3):274–275. [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES