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. 1978 Oct;8(4):465–467. doi: 10.1128/jcm.8.4.465-467.1978

Determination of immunoglobulin A concentrations in human nasal secretions with a serum immunoglobulin A standard.

S B Greenberg, R D Rossen, H R Six, B D Baxter, R B Couch
PMCID: PMC275273  PMID: 102657

Abstract

By quantitative immunodiffusion tests, nasal secretion immunoglobulin A was underestimated by approximately 5.6-fold when the serum 7S immunoglobulin A standard was employed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brunner H., Greenberg H. B., James W. D., Horswood R. L., Couch R. B., Chanock R. M. Antibody to Mycoplasma pneumoniae in nasal secretions and sputa of experimentally infected human volunteers. Infect Immun. 1973 Oct;8(4):612–620. doi: 10.1128/iai.8.4.612-620.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Butler W. T., Rossen R. D., Waldmann T. A. The mechanism of appearance of immunoglobulin A in nasal secretions in man. J Clin Invest. 1967 Dec;46(12):1883–1893. doi: 10.1172/JCI105678. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hosty T. A., Hollenbeck M., Shane S. Intercomparison of results obtained with five commercial diffusion plates supplied for quantitation of immunoglobulins. Clin Chem. 1973 May;19(5):524–526. [PubMed] [Google Scholar]
  4. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  5. Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  6. Mandel M. A., Dvorak K. J., Worman L. W., DeCosse J. J. Immunoglobulin content in the bronchial washings of patients with benign and malignant pulmonary disease. N Engl J Med. 1976 Sep 23;295(13):694–698. doi: 10.1056/NEJM197609232951303. [DOI] [PubMed] [Google Scholar]
  7. McMurray D. N., Rey H., Casazza L. J., Watson R. R. Effect of moderate malnutrition on concentrations of immunoglobulins and enzymes in tears and saliva of young Colombian children. Am J Clin Nutr. 1977 Dec;30(12):1944–1948. doi: 10.1093/ajcn/30.12.1944. [DOI] [PubMed] [Google Scholar]
  8. Reynolds H. Y., Newball H. H. Analysis of proteins and respiratory cells obtained from human lungs by bronchial lavage. J Lab Clin Med. 1974 Oct;84(4):559–573. [PubMed] [Google Scholar]
  9. Rossen R. D., Butler W. T., Cate T. R., Szwed C. F., Couch R. B. Protein composition of nasal secretion during respiratory virus infection. Proc Soc Exp Biol Med. 1965 Aug-Sep;119(4):1169–1176. doi: 10.3181/00379727-119-30406. [DOI] [PubMed] [Google Scholar]
  10. Rossen R. D., Butler W. T., Vannier W. E., Douglas R. G., Jr, Steinberg A. G. The sedimentation and antigenic properties of proteins in nasal and other external secretions. J Immunol. 1966 Dec;97(6):925–938. [PubMed] [Google Scholar]
  11. Rossen R. D., Schade A. L., Butler W. T., Kasel J. A. The proteins in nasal secretion: a longitudinal study of the gammaA-globulin, gammaG-globulin, albumin, siderophilin, and total protein concentrations in nasal washings from adult male volunteers. J Clin Invest. 1966 May;45(5):768–776. doi: 10.1172/JCI105391. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Smith C. B., Purcell R. H., Bellanti J. A., Chanock R. M. Protective effect of antibody to parainfluenza type 1 virus. N Engl J Med. 1966 Nov 24;275(21):1145–1152. doi: 10.1056/NEJM196611242752101. [DOI] [PubMed] [Google Scholar]
  13. Tomasi T. B., Grey H. M. Structure and function of immunoglobulin A. Prog Allergy. 1972;16:81–213. [PubMed] [Google Scholar]
  14. Waldman R. H., Mach J. P., Stella M. M., Rowe D. S. Secretory IgA in human serum. J Immunol. 1970 Jul;105(1):43–47. [PubMed] [Google Scholar]

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