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. 1967 May;93(5):1631–1637. doi: 10.1128/jb.93.5.1631-1637.1967

Comparative Inductive Responses of Two β-Galactosidases of Neurospora

William K Bates a,1, Stephen C Hedman a,2, Dow O Woodward a
PMCID: PMC276659  PMID: 6025447

Abstract

The activities of the two β-galactosidases of Neurospora increased in response to the presence of lactose or galactose. d-Xylose preferentially induced higher levels of activity in one of these enzymes. The initial period of the inductive response was examined in cultures transferred from noninducing to inducing media. Variations in the ratio of activities of these enzymes during this induction period indicate that their induction was not coordinate. The induction of the β-galactosidases of Neurospora was less sensitive to low concentrations of inducers than was the induction of the β-galactosidase of bacteria; the time lag of induction was greater in the eucaryotic organism, and the maximal induction of active enzyme was less than that observed in bacteria.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ames B. N., Garry B. COORDINATE REPRESSION OF THE SYNTHESIS OF FOUR HISTIDINE BIOSYNTHETIC ENZYMES BY HISTIDINE. Proc Natl Acad Sci U S A. 1959 Oct;45(10):1453–1461. doi: 10.1073/pnas.45.10.1453. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BATES W. K., WOODWARD D. O. NEUROSPORA BETA-GALACTOSIDASE: EVIDENCE FOR A SECOND ENZYME. Science. 1964 Nov 6;146(3645):777–778. doi: 10.1126/science.146.3645.777. [DOI] [PubMed] [Google Scholar]
  3. JACOB F., MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318–356. doi: 10.1016/s0022-2836(61)80072-7. [DOI] [PubMed] [Google Scholar]
  4. LANDMAN O. E., BONNER D. M. Neurospora lactase. I. Properties of lactase preparations from a lactose utilizing and a lactose non-utilizing strain. Arch Biochem Biophys. 1952 Dec;41(2):253–265. doi: 10.1016/0003-9861(52)90454-2. [DOI] [PubMed] [Google Scholar]
  5. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]

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