Abstract
Faine, S. (University of Sydney, Sydney, Australia), and J. van der Hoeden. Virulence-linked colonial and morphological variation in Leptospira. J. Bacteriol. 88:1493–1496. 1964.—Large-colony typical hooked Leptospira icterohaemorrhagiae was virulent for hamsters and guinea pigs. On cultivation, it was gradually replaced by a serologically identical small-colony avirulent straight mutant. The hooked virulent form was selected in vivo.
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